# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1916113 | 96 | Activity | 0 | ALA1918247 | Not Active | Homo sapiens | |||||
2. | ALA1916113 | 96 | Activity | 0 | ALA1918246 | Active | Rattus norvegicus | |||||
3. | ALA1916113 | 96 | ID50 | = | 1.19 | mg kg-1 | ALA1918245 | mg.kg-1 | Rattus norvegicus | |||
4. | ALA1916113 | 96 | Activity | = | 42.6 | % | ALA1918244 | % | Rattus norvegicus | |||
5. | ALA1916113 | 96 | Activity | = | 62.4 | % | ALA1919373 | % | Rattus norvegicus | |||
6. | ALA1916113 | 96 | Papp | 0 | ALA1919369 | permeable | Canis lupus familiaris | |||||
7. | ALA1916113 | 96 | Papp | 0 | ALA1919368 | permeable | Canis lupus familiaris | |||||
8. | ALA1916113 | 96 | FC | = | 1.9 | ALA1919367 | Mus musculus | |||||
9. | ALA1916113 | 96 | Activity | 0 | ALA1919366 | Active | Rattus norvegicus | |||||
10. | ALA1916113 | 96 | MED | = | 0.075 | mg kg-1 | ALA1919365 | mg kg-1 | Rattus norvegicus | |||
11. | ALA1916113 | 96 | MED | = | 0.075 | mg kg-1 | ALA1919364 | mg kg-1 | Rattus norvegicus | |||
12. | ALA1916113 | 96 | IC50 | = | 5.05 | uM | ALA1919363 | 5.30 | nM | Homo sapiens | ||
13. | ALA1916113 | 96 | IC50 | = | 150 | nM | ALA1919362 | 6.82 | nM | Homo sapiens | ||
14. | ALA1916113 | 96 | Drug uptake | > | 90 | % | ALA1919361 | % | ||||
15. | ALA1916113 | 96 | AUC | = | 3638 | hr.ng/ml | ALA1919360 | ng.hr.mL-1 | Rattus norvegicus | |||
16. | ALA1916113 | 96 | Activity | 0 | ALA1919359 | Dose-dependent effect | Mus musculus | |||||
17. | ALA1916113 | 96 | Activity | 0 | ALA1919358 | Dose-dependent effect | Mus musculus | |||||
18. | ALA1916113 | 96 | FC | = | 4.9 | ALA1919357 | Mus musculus | |||||
19. | ALA1916113 | 96 | AUC | = | 2372 | hr.ng/ml | ALA1919356 | ng.hr.mL-1 | Rattus norvegicus | |||
20. | ALA1916113 | 96 | Vdss | = | 6 | L/Kg | ALA1919355 | L.kg-1 | Canis lupus familiaris |