# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1916123 | 106 | Activity | = | 25.2 | % | ALA1918244 | % | Rattus norvegicus | |||
2. | ALA1916123 | 106 | Activity | = | 39.3 | % | ALA1919373 | % | Rattus norvegicus | |||
3. | ALA1916123 | 106 | MED | = | 0.05 | mg kg-1 | ALA1919365 | mg kg-1 | Rattus norvegicus | |||
4. | ALA1916123 | 106 | MED | = | 0.05 | mg kg-1 | ALA1919364 | mg kg-1 | Rattus norvegicus | |||
5. | ALA1916123 | 106 | Drug uptake | > | 90 | % | ALA1919361 | % | ||||
6. | ALA1916123 | 106 | AUC | = | 8852 | hr.ng/ml | ALA1919360 | ng.hr.mL-1 | Rattus norvegicus | |||
7. | ALA1916123 | 106 | AUC | = | 3279 | hr.ng/ml | ALA1919356 | ng.hr.mL-1 | Rattus norvegicus | |||
8. | ALA1916123 | 106 | Vdss | = | 1.6 | L/Kg | ALA1919353 | L.kg-1 | Canis lupus familiaris | |||
9. | ALA1916123 | 106 | Vdss | = | 1.3 | L/Kg | ALA1919351 | L.kg-1 | Rattus norvegicus | |||
10. | ALA1916123 | 106 | CL | = | 8 | ml/min.kg | ALA1919171 | mL.min-1.kg-1 | Canis lupus familiaris | |||
11. | ALA1916123 | 106 | CL | = | 14 | ml/min.kg | ALA1919169 | mL.min-1.kg-1 | Rattus norvegicus | |||
12. | ALA1916123 | 106 | beta t1/2 | = | 3.4 | hr | ALA1919166 | hr | Canis lupus familiaris | |||
13. | ALA1916123 | 106 | beta t1/2 | = | 1.3 | hr | ALA1919164 | hr | Rattus norvegicus | |||
14. | ALA1916123 | 106 | F | = | 100 | % | ALA1919160 | % | Canis lupus familiaris | |||
15. | ALA1916123 | 106 | F | = | 25 | % | ALA1919158 | % | Rattus norvegicus | |||
16. | ALA1916123 | 106 | t1/2 | = | 16 | min | ALA1919156 | hr | ||||
17. | ALA1916123 | 106 | t1/2 | > | 30 | min | ALA1919155 | hr | ||||
18. | ALA1916123 | 106 | Ratio IC50 | > | 500 | ALA1919154 | ||||||
19. | ALA1916123 | 106 | Ratio IC50 | > | 500 | ALA1919153 | ||||||
20. | ALA1916123 | 106 | IC50 | = | 4870 | nM | ALA1919144 | 5.31 | nM | Homo sapiens |