| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA1935291 | 26, MMP118 | IC50 | = | 1 | nM | ALA1937507 | 9.00 | nM | Homo sapiens | ||
| 2. | ALA1935291 | 26, MMP118 | MED | = | 5 | mg kg-1 | ALA1936232 | mg kg-1 | Mus musculus | |||
| 3. | ALA1935291 | 26, MMP118 | INH | > | 50 | % | ALA1936231 | % | Mus musculus | |||
| 4. | ALA1935291 | 26, MMP118 | INH | > | 50 | % | ALA1936831 | % | Mus musculus | |||
| 5. | ALA1935291 | 26, MMP118 | INH | = | 65.22 | % | ALA1936830 | % | Mus musculus | |||
| 6. | ALA1935291 | 26, MMP118 | INH | = | 38.63 | % | ALA1936829 | % | Mus musculus | |||
| 7. | ALA1935291 | 26, MMP118 | INH | = | 24.9 | % | ALA1936828 | % | Mus musculus | |||
| 8. | ALA1935291 | 26, MMP118 | F | = | 63 | % | ALA1936827 | % | Mus musculus | |||
| 9. | ALA1935291 | 26, MMP118 | AUC | = | 20317 | hr.ng/ml | ALA1936826 | ng.hr.mL-1 | Mus musculus | |||
| 10. | ALA1935291 | 26, MMP118 | Cmax | = | 5550 | ng/ml | ALA1937527 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 11. | ALA1935291 | 26, MMP118 | t1/2 | = | 2.9 | hr | ALA1937526 | hr | Mus musculus | |||
| 12. | ALA1935291 | 26, MMP118 | CL | = | 5 | ml/min.kg | ALA1937525 | mL.min-1.kg-1 | Mus musculus | |||
| 13. | ALA1935291 | 26, MMP118 | Vdss | = | 0.8 | L/Kg | ALA1937524 | L.kg-1 | Mus musculus | |||
| 14. | ALA1935291 | 26, MMP118 | IC50 | = | 5.4 | nM | ALA1937523 | 8.27 | nM | |||
| 15. | ALA1935291 | 26, MMP118 | IC50 | = | 244 | nM | ALA1937522 | 6.61 | nM | |||
| 16. | ALA1935291 | 26, MMP118 | IC50 | = | 70 | nM | ALA1937521 | 7.16 | nM | Canis familiaris | ||
| 17. | ALA1935291 | 26, MMP118 | IC50 | = | 57 | nM | ALA1937520 | 7.24 | nM | Oryctolagus cuniculus | ||
| 18. | ALA1935291 | 26, MMP118 | IC50 | = | 85 | nM | ALA1937519 | 7.07 | nM | Mus musculus | ||
| 19. | ALA1935291 | 26, MMP118 | INH | 0 | ALA1937518 | Not Active | % | Homo sapiens | ||||
| 20. | ALA1935291 | 26, MMP118 | Activity | 0 | ALA1937517 | Non-toxic | Salmonella enterica subsp. enterica serovar Typhimurium |
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