# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1940315 | 21, Diastereomer 1 | LogD7.4 | 1.4 | ALA3301363 | |||||||
2. | ALA1940315 | 21, Diastereomer 1 | CLH | < | 2 | uL/min | ALA1943061 | uL/min | Homo sapiens | |||
3. | ALA1940315 | 21, Diastereomer 1 | Ae | < | 1 | % | ALA1943060 | % | Rattus norvegicus | |||
4. | ALA1940315 | 21, Diastereomer 1 | F | = | 21 | % | ALA1943059 | % | Canis lupus familiaris | |||
5. | ALA1940315 | 21, Diastereomer 1 | F | = | 35 | % | ALA1943057 | % | Rattus norvegicus | |||
6. | ALA1940315 | 21, Diastereomer 1 | F | = | 0 | % | ALA1943057 | % | Rattus norvegicus | |||
7. | ALA1940315 | 21, Diastereomer 1 | Fabs | = | 28 | ALA1943703 | Canis lupus familiaris | |||||
8. | ALA1940315 | 21, Diastereomer 1 | IC50 | > | 10 | uM | ALA1943056 | nM | Homo sapiens | |||
9. | ALA1940315 | 21, Diastereomer 1 | IC50 | > | 10 | uM | ALA1942968 | nM | Homo sapiens | |||
10. | ALA1940315 | 21, Diastereomer 1 | INH | > | 10 | uM | ALA1942959 | uM | Homo sapiens | |||
11. | ALA1940315 | 21, Diastereomer 1 | INH | > | 10 | uM | ALA1942960 | uM | Homo sapiens | |||
12. | ALA1940315 | 21, Diastereomer 1 | Fu | = | 33 | % | ALA1942961 | |||||
13. | ALA1940315 | 21, Diastereomer 1 | IC50 | > | 100 | uM | ALA1942962 | nM | Homo sapiens | |||
14. | ALA1940315 | 21, Diastereomer 1 | EC50 | = | 116 | uM | ALA1942963 | nM | ||||
15. | ALA1940315 | 21, Diastereomer 1 | CL | = | 13 | ml/min.kg | ALA1942964 | mL.min-1.kg-1 | Canis lupus familiaris | |||
16. | ALA1940315 | 21, Diastereomer 1 | t1/2 | = | 5 | hr | ALA1942965 | hr | Canis lupus familiaris | |||
17. | ALA1940315 | 21, Diastereomer 1 | Vdss | = | 3.9 | L/Kg | ALA1942966 | L.kg-1 | Canis lupus familiaris | |||
18. | ALA1940315 | 21, Diastereomer 1 | IC50 | > | 10 | uM | ALA1942967 | nM | Homo sapiens | |||
19. | ALA1940315 | 21, Diastereomer 1 | Papp | = | 1.3 | ucm/s | ALA1942956 | ucm/s | Homo sapiens | |||
20. | ALA1940315 | 21, Diastereomer 1 | Papp | = | 43.5 | ucm/s | ALA1942957 | ucm/s | Homo sapiens |