Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA1946956	42, BDM41906	IC50	=	0.4	uM	ALA4434519	6.40		nM	Mycobacterium tuberculosis
2.	ALA1946956	42, BDM41906	CC50	>	20	uM	ALA4296191		Median N= 2; Maxinhib 22.4 Pct	nM	Homo sapiens
3.	ALA1946956	42, BDM41906	HC10	>	20	uM	ALA4296784		Median N= 2; Maxinhib 13.9 Pct	uM
4.	ALA1946956	42, BDM41906	MIC	>	20	uM	ALA4296184		Median N= 2; Maxinhib 10.8 Pct	nM	Staphylococcus aureus
5.	ALA1946956	42, BDM41906	MIC	>	20	uM	ALA4296802		Median N= 2; Maxinhib 5.2 Pct	nM	Pseudomonas aeruginosa
6.	ALA1946956	42, BDM41906	MIC	>	20	uM	ALA4296188		Median N= 2; Maxinhib 15.6 Pct	nM	Acinetobacter baumannii
7.	ALA1946956	42, BDM41906	MIC	>	20	uM	ALA4296187		Median N= 2; Maxinhib 19.4 Pct	nM	Pseudomonas aeruginosa
8.	ALA1946956	42, BDM41906	MIC	>	20	uM	ALA4296186		Median N= 2; Maxinhib 15.3 Pct	nM	Klebsiella pneumoniae
9.	ALA1946956	42, BDM41906	MIC	>	20	uM	ALA4296185		Median N= 2; Maxinhib 4.2 Pct	nM	Escherichia coli
10.	ALA1946956	42, BDM41906	MIC	>	20	uM	ALA4296190		Median N= 2; Maxinhib 6.8 Pct	nM	Cryptococcus neoformans
11.	ALA1946956	42, BDM41906	MIC	>	20	uM	ALA4296189		Median N= 2; Maxinhib 3.9 Pct	nM	Candida albicans
12.	ALA1946956	42, BDM41906	Ratio	>	30		ALA1948070
13.	ALA1946956	42, BDM41906	AUC	=	98.6	ug/ml.hr	ALA1947976			ng.hr.mL-1	Mus musculus
14.	ALA1946956	42, BDM41906	CLH	=	15	microL/min/mg	ALA1947971			mL.min-1.g-1	Mus musculus
15.	ALA1946956	42, BDM41906	t1/2	=	81	min	ALA1947970			hr	Mus musculus
16.	ALA1946956	42, BDM41906	solubility	=	410	ug ml-1	ALA1947972			ug.mL-1
17.	ALA1946956	42, BDM41906	INH		0		ALA1947973		Dose-dependent effect	%	Mycobacterium tuberculosis
18.	ALA1946956	42, BDM41906	IC50	=	0.4	uM	ALA1947973	6.40		nM	Mycobacterium tuberculosis
19.	ALA1946956	42, BDM41906	EC50	=	0.06	uM	ALA1947974	7.22		nM	Mycobacterium tuberculosis