# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1956115 | 1a | MIC | = | 1 | ug ml-1 | ALA2166988 | ug.mL-1 | Pseudomonas aeruginosa | |||
2. | ALA1956115 | 1a | MIC | = | 1 | ug ml-1 | ALA2166989 | ug.mL-1 | Pseudomonas aeruginosa | |||
3. | ALA1956115 | 1a | logD | = | 2.24 | ALA2166996 | ||||||
4. | ALA1956115 | 1a | MIC90 | = | 2 | ug ml-1 | ALA1960309 | ug.mL-1 | Pseudomonas aeruginosa | |||
5. | ALA1956115 | 1a | MIC50 | = | 0.5 | ug ml-1 | ALA1960309 | ug.mL-1 | Pseudomonas aeruginosa | |||
6. | ALA1956115 | 1a | PD50 | = | 63.4 | mg kg-1 | ALA1960308 | mg kg-1 | Pseudomonas aeruginosa | |||
7. | ALA1956115 | 1a | FC | = | 6.2 | ALA1960307 | Pseudomonas aeruginosa | |||||
8. | ALA1956115 | 1a | ED50 | = | 35 | mg kg-1 | ALA1960306 | mg.kg-1 | Pseudomonas aeruginosa | |||
9. | ALA1956115 | 1a | Fu | = | 2 | % | ALA1960305 | Homo sapiens | ||||
10. | ALA1956115 | 1a | t1/2 | = | 3.2 | hr | ALA1960304 | hr | Rattus norvegicus | |||
11. | ALA1956115 | 1a | AUC | = | 2.8 | microg.hr/mL | ALA1960303 | ng.hr.mL-1 | Rattus norvegicus | |||
12. | ALA1956115 | 1a | Vdss | = | 2.7 | L/Kg | ALA1960302 | L.kg-1 | Rattus norvegicus | |||
13. | ALA1956115 | 1a | CL | = | 58 | ml/min.kg | ALA1960301 | mL.min-1.kg-1 | Rattus norvegicus | |||
14. | ALA1956115 | 1a | IC50 | = | 18 | uM | ALA1960300 | 4.75 | nM | |||
15. | ALA1956115 | 1a | INH | > | 50 | % | ALA1960299 | % | ||||
16. | ALA1956115 | 1a | Ki | = | 250 | nM | ALA1960298 | 6.60 | nM | Homo sapiens | ||
17. | ALA1956115 | 1a | IC50 | = | 340 | nM | ALA1960298 | 6.47 | nM | Homo sapiens | ||
18. | ALA1956115 | 1a | INH | > | 50 | % | ALA1960297 | % | Homo sapiens | |||
19. | ALA1956115 | 1a | Ki | > | 10 | uM | ALA1960137 | nM | Homo sapiens | |||
20. | ALA1956115 | 1a | Ki | > | 10 | uM | ALA1960136 | nM | Homo sapiens |