# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1956278 | 29, DSM322 | IC50 | = | 140 | nM | ALA3705388 | 6.85 | 318909 | nM | Plasmodium falciparum (isolate 3D7) | |
2. | ALA1956278 | 29, DSM322 | IC50 | = | 0.14 | uM | ALA1961096 | 6.85 | nM | Plasmodium falciparum | ||
3. | ALA1956278 | 29, DSM322 | IC50 | = | 2.6 | uM | ALA1961097 | 5.58 | nM | |||
4. | ALA1956278 | 29, DSM322 | IC50 | > | 100 | uM | ALA1961098 | nM | Homo sapiens | |||
5. | ALA1956278 | 29, DSM322 | EC50 | = | 0.15 | uM | ALA1961099 | 6.82 | nM | Plasmodium falciparum | ||
6. | ALA1956278 | 29, DSM322 | logD | = | 3.3 | ALA1961102 | ||||||
7. | ALA1956278 | 29, DSM322 | solubility | = | 38 | uM | ALA1961103 | nM | ||||
8. | ALA1956278 | 29, DSM322 | PPB | = | 92.8 | % | ALA1960900 | % | Homo sapiens | |||
9. | ALA1956278 | 29, DSM322 | CLH | < | 5 | microL/min/mg | ALA1960902 | mL.min-1.g-1 | Homo sapiens | |||
10. | ALA1956278 | 29, DSM322 | CLH | = | 8.6 | microL/min/mg | ALA1960903 | mL.min-1.g-1 | Mus musculus |