# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1956283 | 35, DSM254 | IC50 | = | 28 | nM | ALA3705388 | 7.55 | 318916 | nM | Plasmodium falciparum (isolate 3D7) | |
2. | ALA1956283 | 35, DSM254 | IC50 | = | 0.038 | uM | ALA1961096 | 7.42 | nM | Plasmodium falciparum | ||
3. | ALA1956283 | 35, DSM254 | IC50 | = | 1.7 | uM | ALA1961097 | 5.77 | nM | |||
4. | ALA1956283 | 35, DSM254 | IC50 | > | 100 | uM | ALA1961098 | nM | Homo sapiens | |||
5. | ALA1956283 | 35, DSM254 | EC50 | = | 0.05 | uM | ALA1961099 | 7.30 | nM | Plasmodium falciparum | ||
6. | ALA1956283 | 35, DSM254 | logD | = | 3 | ALA1961102 | ||||||
7. | ALA1956283 | 35, DSM254 | solubility | = | 77 | uM | ALA1961103 | nM | ||||
8. | ALA1956283 | 35, DSM254 | PPB | = | 87.9 | % | ALA1960900 | % | Homo sapiens | |||
9. | ALA1956283 | 35, DSM254 | CLH | = | 16 | microL/min/mg | ALA1960902 | mL.min-1.g-1 | Homo sapiens | |||
10. | ALA1956283 | 35, DSM254 | CLH | = | 62.8 | microL/min/mg | ALA1960903 | mL.min-1.g-1 | Mus musculus |