# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1956290 | 43, DSM195 | IC50 | = | 0.023 | uM | ALA5246246 | 7.64 | nM | Plasmodium falciparum | ||
2. | ALA1956290 | 43, DSM195 | IC50 | = | 35 | nM | ALA3705388 | 7.46 | 318876 | nM | Plasmodium falciparum (isolate 3D7) | |
3. | ALA1956290 | 43, DSM195 | IC50 | = | 0.035 | uM | ALA3878218 | 7.46 | nM | |||
4. | ALA1956290 | 43, DSM195 | IC50 | > | 100 | uM | ALA3296347 | nM | Homo sapiens | |||
5. | ALA1956290 | 43, DSM195 | IC50 | = | 86 | uM | ALA3296349 | 4.07 | nM | |||
6. | ALA1956290 | 43, DSM195 | IC50 | = | 9.7 | uM | ALA3296344 | 5.01 | nM | Mus musculus | ||
7. | ALA1956290 | 43, DSM195 | IC50 | = | 3.5 | uM | ALA3296348 | 5.46 | nM | Rattus norvegicus | ||
8. | ALA1956290 | 43, DSM195 | IC50 | = | 0.035 | uM | ALA3296346 | 7.46 | nM | Plasmodium falciparum | ||
9. | ALA1956290 | 43, DSM195 | IC50 | = | 0.006 | uM | ALA3296345 | 8.20 | nM | Plasmodium falciparum | ||
10. | ALA1956290 | 43, DSM195 | IC50 | = | 0.035 | uM | ALA1961096 | 7.46 | nM | Plasmodium falciparum | ||
11. | ALA1956290 | 43, DSM195 | IC50 | = | 1.3 | uM | ALA1961097 | 5.89 | nM | |||
12. | ALA1956290 | 43, DSM195 | IC50 | > | 100 | uM | ALA1961098 | nM | Homo sapiens | |||
13. | ALA1956290 | 43, DSM195 | EC50 | = | 0.073 | uM | ALA1961099 | 7.14 | nM | Plasmodium falciparum | ||
14. | ALA1956290 | 43, DSM195 | logD | 0 | ALA1961102 | Not Determined | ||||||
15. | ALA1956290 | 43, DSM195 | solubility | 0 | ALA1961103 | Not Determined | ||||||
16. | ALA1956290 | 43, DSM195 | PPB | 0 | ALA1960900 | Not Determined | % | Homo sapiens | ||||
17. | ALA1956290 | 43, DSM195 | CLH | < | 5 | microL/min/mg | ALA1960902 | mL.min-1.g-1 | Homo sapiens | |||
18. | ALA1956290 | 43, DSM195 | CLH | < | 6 | microL/min/mg | ALA1960903 | mL.min-1.g-1 | Mus musculus |