# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1963594 | 6 | EC90 | = | 640 | nM | ALA2160409 | nM | Plasmodium falciparum | |||
2. | ALA1963594 | 6 | EC90 | = | 1300 | nM | ALA2160408 | nM | Plasmodium falciparum | |||
3. | ALA1963594 | 6 | Activity | 0 | ALA2160596 | Non-toxic | Homo sapiens | |||||
4. | ALA1963594 | 6 | Activity | 0 | ALA2160595 | Non-toxic | Homo sapiens | |||||
5. | ALA1963594 | 6 | Activity | 0 | ALA2160594 | Non-toxic | Homo sapiens | |||||
6. | ALA1963594 | 6 | Activity | 0 | ALA2160593 | Non-toxic | Homo sapiens | |||||
7. | ALA1963594 | 6 | MTD | = | 10 | mg kg-1 | ALA2160437 | mg kg-1 | Mus musculus | |||
8. | ALA1963594 | 6 | CL/F | = | 60268 | ml/hr.kg | ALA2160433 | mL.min-1.kg-1 | Mus musculus | |||
9. | ALA1963594 | 6 | CL/F | 0 | ALA2160432 | Not Determined | Mus musculus | |||||
10. | ALA1963594 | 6 | Vz/F | = | 271.8 | L/Kg | ALA2160430 | L.kg-1 | Mus musculus | |||
11. | ALA1963594 | 6 | Vz/F | 0 | ALA2160429 | Not Determined | Mus musculus | |||||
12. | ALA1963594 | 6 | AUC | = | 6486.8 | nM/ml | ALA2160427 | nM/ml | Mus musculus | |||
13. | ALA1963594 | 6 | AUC | 0 | ALA2160426 | Not Determined | Mus musculus | |||||
14. | ALA1963594 | 6 | Tmax | = | 0.5 | hr | ALA2160424 | hr | Mus musculus | |||
15. | ALA1963594 | 6 | Tmax | = | 8 | hr | ALA2160423 | hr | Mus musculus | |||
16. | ALA1963594 | 6 | Cmax | = | 866.5 | nM | ALA2160421 | nM | Mus musculus | |||
17. | ALA1963594 | 6 | Cmax | = | 301.8 | nM | ALA2160420 | nM | Mus musculus | |||
18. | ALA1963594 | 6 | CLH | = | 38 | ml/min.kg | ALA2160419 | mL.min-1.kg-1 | Homo sapiens | |||
19. | ALA1963594 | 6 | CLH | = | 30 | ml/min.kg | ALA2160418 | mL.min-1.kg-1 | Mus musculus | |||
20. | ALA1963594 | 6 | solubility | = | 2.2 | uM | ALA2160417 | nM |