| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA311074 | 87 | pKa_B1 | 7.6 | ALA3301362 | "B1 Functional Group: 1H-perimidin-2-amine; Ionisation Formula: A0B1 (Functional Group: the part of the molecule the pKa refers to; Ionisation formula: AxBy where 'A' refers to acidic centers within the molecule that are appreciably ionised at a pH <= 11 and 'x' equals 0, 1 or 2; and 'B' refers to basic centers within the molecule that are appreciably ionised at a pH >= 2 and 'y' equals 0, 1, 2 or 3)." | ||||||
| 2. | ALA311074 | 87 | LUCIFERASE EXPRESSION CONTROL - IC90 | = | 2.27 | uM | ALA4483863 | uM | Plasmodium berghei | |||
| 3. | ALA311074 | 87 | LUCIFERASE EXPRESSION CONTROL - IC50 | = | 2.27 | uM | ALA4483863 | uM | Plasmodium berghei | |||
| 4. | ALA311074 | 87 | HEPG2TOX ASSAY - CC90 | = | 6.42 | uM | ALA4483864 | uM | Homo sapiens | |||
| 5. | ALA311074 | 87 | HEPG2TOX ASSAY - CC50 | = | 6.42 | uM | ALA4483864 | uM | Homo sapiens | |||
| 6. | ALA311074 | 87 | LUCIFERASE INFECTION ASSAY - IC90 | = | 12.9 | uM | ALA4483863 | uM | Plasmodium berghei | |||
| 7. | ALA311074 | 87 | LUCIFERASE INFECTION ASSAY - IC50 | = | 6.42 | uM | ALA4483863 | uM | Plasmodium berghei | |||
| 8. | ALA311074 | 87 | IC50 | = | 7.8 | uM | ALA994876 | 5.11 | nM | |||
| 9. | ALA311074 | 87 | IC50 | = | 0.8 | uM | ALA991467 | 6.10 | nM | Escherichia coli K-12 | ||
| 10. | ALA311074 | 87 | IC50 | = | 2.3 | uM | ALA994101 | 5.64 | nM | Escherichia coli K-12 | ||
| 11. | ALA311074 | 87 | IC50 | = | 1 | uM | ALA994102 | 6.00 | nM | Escherichia coli K-12 | ||
| 12. | ALA311074 | 87 | IC50 | = | 17 | uM | ALA994866 | 4.77 | nM | |||
| 13. | ALA311074 | 87 | IC50 | = | 0.5 | uM | ALA994877 | 6.30 | nM | |||
| 14. | ALA311074 | 87 | IC50 | = | 1.2 | uM | ALA994867 | 5.92 | nM | |||
| 15. | ALA311074 | 87 | IC50 | = | 1.6 | uM | ALA994868 | 5.80 | nM | |||
| 16. | ALA311074 | 87 | IC50 | = | 2.6 | uM | ALA994869 | 5.58 | nM | |||
| 17. | ALA311074 | 87 | IC50 | = | 1.8 | uM | ALA994870 | 5.75 | nM | |||
| 18. | ALA311074 | 87 | IC50 | = | 0.8 | uM | ALA994871 | 6.10 | nM | Escherichia coli K-12 | ||
| 19. | ALA311074 | 87 | IC50 | = | 0.3 | uM | ALA994878 | 6.52 | nM | |||
| 20. | ALA311074 | 87 | IC50 | = | 1.5 | uM | ALA994872 | 5.82 | nM |
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