| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2011441 | G | CLint | < | 3 | microL/min/mg | ALA3301370 | mL.min-1.g-1 | ||||
| 2. | ALA2011441 | G | pKa_A1 | 4.1 | ALA3301375 | "A1 Functional Group: Sulphonamide; Ionisation Formula: A1B0 (Functional Group: the part of the molecule the pKa refers to; Ionisation formula: AxBy where 'A' refers to acidic centers within the molecule that are appreciably ionised at a pH <= 11 and 'x' equals 0, 1 or 2; and 'B' refers to basic centers within the molecule that are appreciably ionised at a pH >= 2 and 'y' equals 0, 1, 2 or 3)." | ||||||
| 3. | ALA2011441 | G | CLint | < | 3 | microL/min/1E6 cells | ALA3301371 | uL.min-1.(10^6cells)-1 | ||||
| 4. | ALA2011441 | G | LogD7.4 | 0.99 | ALA3301363 | |||||||
| 5. | ALA2011441 | G | PPB | 99.87 | % | ALA3301365 | % | |||||
| 6. | ALA2011441 | G | PPB | 99.8 | % | ALA3301366 | % | |||||
| 7. | ALA2011441 | G | PPB | 98.76 | % | ALA3301367 | % | |||||
| 8. | ALA2011441 | G | PPB | 98.09 | % | ALA3301368 | % | |||||
| 9. | ALA2011441 | G | Solubility | 891.3 | uM | ALA3301364 | nM | |||||
| 10. | ALA2011441 | G | Kd | = | 22.6 | uM | ALA2015428 | 4.65 | nM | Homo sapiens | ||
| 11. | ALA2011441 | G | Activity | 0 | ALA2015426 | Not Active | Homo sapiens | |||||
| 12. | ALA2011441 | G | Activity | 0 | ALA2015425 | Active | Homo sapiens | |||||
| 13. | ALA2011441 | G | Kd | = | 28.6 | uM | ALA2015361 | 4.54 | nM | Homo sapiens | ||
| 14. | ALA2011441 | G | pIC50 | = | 6.7 | ALA4134315 | 6.70 | nM | Homo sapiens | |||
| 15. | ALA2011441 | G | Activity | 0 | ALA4134314 | Not Active | Homo sapiens | |||||
| 16. | ALA2011441 | G | Activity | 0 | ALA4134313 | Not Active | Homo sapiens | |||||
| 17. | ALA2011441 | G | Activity | 0 | ALA4134312 | Not Active | Homo sapiens | |||||
| 18. | ALA2011441 | G | Activity | 0 | ALA4134311 | Not Active | Homo sapiens | |||||
| 19. | ALA2011441 | G | Activity | 0 | ALA4134310 | Not Active | Homo sapiens | |||||
| 20. | ALA2011441 | G | Activity | 0 | ALA4134309 | Not Active | Homo sapiens |
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