# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2028064 | MMV403679 | Ratio | = | 0.606 | ALA2448810 | Plasmodium falciparum | |||||
2. | ALA2028064 | MMV403679 | Motility | 0 | ALA2363031 | Slow, on sides, dark, tegument damage | Schistosoma mansoni | |||||
3. | ALA2028064 | MMV403679 | Motility | = | 1 | ALA2363030 | Slow, on sides, dark | Schistosoma mansoni | ||||
4. | ALA2028064 | MMV403679 | Motility | = | 6 | ALA2363029 | No effect | Schistosoma mansoni | ||||
5. | ALA2028064 | MMV403679 | Toxicity | = | 4 | ALA2363028 | Slow, on sides, dark, tegument damage | Schistosoma mansoni | ||||
6. | ALA2028064 | MMV403679 | Toxicity | = | 3 | ALA2363027 | Slow, on sides, dark | Schistosoma mansoni | ||||
7. | ALA2028064 | MMV403679 | Toxicity | = | 0 | ALA2363026 | No effect | Schistosoma mansoni | ||||
8. | ALA2028064 | MMV403679 | Toxicity | = | 4 | ALA2363025 | Degenerate | Schistosoma mansoni | ||||
9. | ALA2028064 | MMV403679 | Toxicity | = | 1 | ALA2363024 | Dark | Schistosoma mansoni | ||||
10. | ALA2028064 | MMV403679 | Toxicity | = | 1 | ALA2363023 | Dark | Schistosoma mansoni | ||||
11. | ALA2028064 | MMV403679 | Inhibition | = | 48.5 | % | ALA2094262 | % | Mycobacterium tuberculosis | |||
12. | ALA2028064 | MMV403679 | Inhibition | = | 48.2 | % | ALA2094261 | % | Mycobacterium tuberculosis | |||
13. | ALA2028064 | MMV403679 | IC50 | = | 0.305 | uM | ALA2028075 | 6.52 | nM | Trypanosoma brucei rhodesiense | ||
14. | ALA2028064 | MMV403679 | IC50 | = | 0.481 | uM | ALA2028074 | 6.32 | nM | Trypanosoma brucei brucei | ||
15. | ALA2028064 | MMV403679 | IC50 | = | 0.234 | uM | ALA2028073 | 6.63 | nM | Trypanosoma cruzi | ||
16. | ALA2028064 | MMV403679 | EC50 | = | 929 | nM | ALA2028071 | 6.03 | nM | Plasmodium falciparum | ||
17. | ALA2028064 | MMV403679 | IC50 | = | 0.653 | uM | ALA2028077 | 6.18 | nM | Homo sapiens | ||
18. | ALA2028064 | MMV403679 | IC50 | = | 4.32 | uM | ALA2028076 | 5.36 | nM | Leishmania infantum | ||
19. | ALA2028064 | MMV403679 | IC50 | = | 993.8 | nM | ALA3392923 | 6.00 | nM | Plasmodium falciparum | ||
20. | ALA2028064 | MMV403679 | IC50 | > | 1 | uM | ALA3301567 | nM | Plasmodium falciparum (isolate 3D7) |