# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2035632 | 6c | Ratio IC50 | >= | 10 | ALA2038173 | ||||||
2. | ALA2035632 | 6c | Ratio IC50 | >= | 10 | ALA2038172 | ||||||
3. | ALA2035632 | 6c | AUC/dose | = | 1.3 | uM.hr.kg/mg | ALA2038162 | uM.hr.kg/mg | Rattus norvegicus | |||
4. | ALA2035632 | 6c | AUC/dose | = | 1.7 | uM.hr.kg/mg | ALA2038161 | uM.hr.kg/mg | Rattus norvegicus | |||
5. | ALA2035632 | 6c | Cmax | = | 0.8 | uM | ALA2038160 | nM | Rattus norvegicus | |||
6. | ALA2035632 | 6c | Cmax | = | 1.8 | uM | ALA2038159 | nM | Rattus norvegicus | |||
7. | ALA2035632 | 6c | F | = | 77 | % | ALA2038158 | % | Rattus norvegicus | |||
8. | ALA2035632 | 6c | t1/2 | = | 1 | hr | ALA2038157 | hr | Rattus norvegicus | |||
9. | ALA2035632 | 6c | t1/2 | = | 1 | hr | ALA2038156 | hr | Rattus norvegicus | |||
10. | ALA2035632 | 6c | Vd | = | 3.8 | L/Kg | ALA2038155 | L.kg-1 | Rattus norvegicus | |||
11. | ALA2035632 | 6c | CL | = | 1837 | ml/hr.kg | ALA2038016 | mL.min-1.kg-1 | Rattus norvegicus | |||
12. | ALA2035632 | 6c | Cp | = | 5 | uM | ALA2038015 | uM | Mus musculus | |||
13. | ALA2035632 | 6c | Cp | = | 13 | uM | ALA2038014 | uM | Mus musculus | |||
14. | ALA2035632 | 6c | IC50 | = | 1051 | nM | ALA2038013 | 5.98 | nM | |||
15. | ALA2035632 | 6c | permeability | = | 499 | nm/s | ALA2038012 | nm/s | Canis lupus familiaris | |||
16. | ALA2035632 | 6c | IC50 | = | 115 | nM | ALA2038011 | 6.94 | nM | Homo sapiens | ||
17. | ALA2035632 | 6c | IC50 | = | 10 | nM | ALA2038010 | 8.00 | nM | Homo sapiens | ||
18. | ALA2035632 | 6c | IC50 | = | 68 | nM | ALA2038009 | 7.17 | nM | Homo sapiens | ||
19. | ALA2035632 | 6c | IC50 | = | 9 | nM | ALA2038008 | 8.05 | nM | Homo sapiens | ||
20. | ALA2035632 | 6c | IC50 | = | 9 | nM | ALA4044916 | 8.05 | nM | Homo sapiens |