# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2042441 | 12b | IC50 | = | 110 | nM | ALA3705321 | 6.96 | 218691 | nM | Hepatitis C virus genotype 1b (strain HC-J4) (HCV) | |
2. | ALA2042441 | 12b | Ratio | = | 150 | ALA2043766 | ||||||
3. | ALA2042441 | 12b | Drug uptake | = | 3743 | ng/g | ALA2043765 | ng/g | Rattus norvegicus | |||
4. | ALA2042441 | 12b | F | = | 40 | % | ALA2043764 | % | Rattus norvegicus | |||
5. | ALA2042441 | 12b | t1/2 | = | 0.4 | hr | ALA2043763 | hr | Rattus norvegicus | |||
6. | ALA2042441 | 12b | Vdss | = | 2.4 | L/Kg | ALA2043762 | L.kg-1 | Rattus norvegicus | |||
7. | ALA2042441 | 12b | CL | = | 7.4 | L/hr/kg | ALA2043761 | mL.min-1.kg-1 | Rattus norvegicus | |||
8. | ALA2042441 | 12b | Drug metabolism | = | 67 | % | ALA2043760 | % | Homo sapiens | |||
9. | ALA2042441 | 12b | Drug metabolism | = | 63 | % | ALA2043759 | % | Rattus norvegicus | |||
10. | ALA2042441 | 12b | EC50 | = | 0.79 | uM | ALA2043755 | 6.10 | nM | Hepacivirus hominis |