# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2048287 | 17 | Activity | 0 | ALA2050033 | Active | Mus musculus | |||||
2. | ALA2048287 | 17 | Activity | 0 | ALA2050012 | Active | Mus musculus | |||||
3. | ALA2048287 | 17 | Activity | 0 | ALA2050011 | Active | Mus musculus | |||||
4. | ALA2048287 | 17 | F | = | 32.5 | % | ALA2050010 | % | Rattus norvegicus | |||
5. | ALA2048287 | 17 | AUClast | = | 11 | hr.microg/ml | ALA2050009 | ng.hr.mL-1 | Rattus norvegicus | |||
6. | ALA2048287 | 17 | Cmax | = | 1.4 | ng/ml | ALA2050006 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
7. | ALA2048287 | 17 | beta t1/2 | = | 5.46 | hr | ALA2050008 | hr | Rattus norvegicus | |||
8. | ALA2048287 | 17 | Vdss | = | 0.734 | L/Kg | ALA2050007 | L.kg-1 | Rattus norvegicus | |||
9. | ALA2048287 | 17 | CL | = | 0.083 | L/hr/kg | ALA2049915 | mL.min-1.kg-1 | Rattus norvegicus | |||
10. | ALA2048287 | 17 | t1/2 | > | 60 | min | ALA2049914 | hr | Homo sapiens | |||
11. | ALA2048287 | 17 | t1/2 | > | 60 | min | ALA2049913 | hr | Rattus norvegicus | |||
12. | ALA2048287 | 17 | t1/2 | > | 60 | min | ALA2049910 | hr | Mus musculus | |||
13. | ALA2048287 | 17 | EC50 | = | 15 | nM | ALA2049912 | 7.82 | nM | Homo sapiens | ||
14. | ALA2048287 | 17 | EC50 | = | 11 | nM | ALA2049912 | 7.96 | nM | Homo sapiens | ||
15. | ALA2048287 | 17 | EC50 | = | 462 | nM | ALA2049911 | 6.33 | nM | Homo sapiens | ||
16. | ALA2048287 | 17 | EC50 | = | 239 | nM | ALA2049911 | 6.62 | nM | Homo sapiens | ||
17. | ALA2048287 | 17 | EC50 | > | 100000 | nM | ALA2049909 | nM | Homo sapiens | |||
18. | ALA2048287 | 17 | EC50 | > | 100000 | nM | ALA2049909 | nM | Homo sapiens | |||
19. | ALA2048287 | 17 | EC50 | > | 100000 | nM | ALA2049905 | nM | Homo sapiens | |||
20. | ALA2048287 | 17 | EC50 | > | 100000 | nM | ALA2049905 | nM | Homo sapiens |