| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2057803 | 10 | BPR | = | 0.8 | ALA2060608 | ||||||
| 2. | ALA2057803 | 10 | Activity | 0 | ALA2060586 | Non-toxic | Rattus norvegicus | |||||
| 3. | ALA2057803 | 10 | Activity | 0 | ALA2060588 | Dose-dependent effect | Rattus norvegicus | |||||
| 4. | ALA2057803 | 10 | F | = | 55 | % | ALA2060589 | % | Canis lupus familiaris | |||
| 5. | ALA2057803 | 10 | Cmax | = | 368 | ng/ml | ALA2060590 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Canis lupus familiaris | ||
| 6. | ALA2057803 | 10 | AUC | = | 1480 | ng.hr/ml | ALA2060591 | ng.hr.mL-1 | Canis lupus familiaris | |||
| 7. | ALA2057803 | 10 | t1/2 | = | 4.2 | hr | ALA2060592 | hr | Canis lupus familiaris | |||
| 8. | ALA2057803 | 10 | Vd | = | 6.8 | L/Kg | ALA2060593 | L.kg-1 | Canis lupus familiaris | |||
| 9. | ALA2057803 | 10 | CL | = | 21 | ml/min.kg | ALA2060594 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 10. | ALA2057803 | 10 | Ratio | = | 1.1 | ALA2060595 | Canis lupus familiaris | |||||
| 11. | ALA2057803 | 10 | permeability | = | 52 | ucm/s | ALA2060596 | ucm/s | Canis lupus familiaris | |||
| 12. | ALA2057803 | 10 | permeability | = | 47 | ucm/s | ALA2060597 | ucm/s | Canis lupus familiaris | |||
| 13. | ALA2057803 | 10 | Ratio | = | 1.3 | ALA2060598 | Canis lupus familiaris | |||||
| 14. | ALA2057803 | 10 | permeability | = | 56 | ucm/s | ALA2060599 | ucm/s | Canis lupus familiaris | |||
| 15. | ALA2057803 | 10 | permeability | = | 42 | ucm/s | ALA2060600 | ucm/s | Canis lupus familiaris | |||
| 16. | ALA2057803 | 10 | Cmax | = | 46 | ng/ml | ALA2060601 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 17. | ALA2057803 | 10 | AUC | = | 158 | ng.hr/ml | ALA2060602 | ng.hr.mL-1 | Rattus norvegicus | |||
| 18. | ALA2057803 | 10 | t1/2 | = | 2.8 | hr | ALA2060603 | hr | Rattus norvegicus | |||
| 19. | ALA2057803 | 10 | solubility | = | 0.06 | mg/ml | ALA2060604 | ug.mL-1 | ||||
| 20. | ALA2057803 | 10 | IC50 | > | 10 | uM | ALA2060606 | nM | Homo sapiens |
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