# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2059865 | 11f | INH | 0 | ALA2060780 | Not Active | % | Homo sapiens | ||||
2. | ALA2059865 | 11f | F | = | 83 | % | ALA2060779 | % | Mus musculus | |||
3. | ALA2059865 | 11f | t1/2 | = | 1 | hr | ALA2060778 | hr | Mus musculus | |||
4. | ALA2059865 | 11f | AUC | = | 12535 | ug.hr/L | ALA2060777 | ng.hr.mL-1 | Mus musculus | |||
5. | ALA2059865 | 11f | Vdss | = | 0.5 | L/Kg | ALA2060776 | L.kg-1 | Mus musculus | |||
6. | ALA2059865 | 11f | CL | = | 8.3 | ml/min.kg | ALA2060775 | mL.min-1.kg-1 | Mus musculus | |||
7. | ALA2059865 | 11f | Fu | = | 5.6 | % | ALA2060774 | Homo sapiens | ||||
8. | ALA2059865 | 11f | solubility | = | 25 | uM | ALA2060773 | nM | ||||
9. | ALA2059865 | 11f | IC50 | = | 2.7 | uM | ALA2060772 | 5.57 | nM | Homo sapiens | ||
10. | ALA2059865 | 11f | EC50 | = | 0.013 | uM | ALA2060771 | 7.89 | nM | Homo sapiens | ||
11. | ALA2059865 | 11f | IC50 | < | 0.012 | uM | ALA2061994 | nM | Homo sapiens | |||
12. | ALA2059865 | 11f | PPB | 94.06 | % | ALA3301365 | % | |||||
13. | ALA2059865 | 11f | LogD7.4 | 3.01 | ALA3301363 | |||||||
14. | ALA2059865 | 11f | PPB | 86.59 | % | ALA3301367 | % | |||||
15. | ALA2059865 | 11f | inhibition | = | -0.2 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
16. | ALA2059865 | 11f | Inhibition | = | 4.524 | % | ALA4495582 | % | Severe acute respiratory syndrome coronavirus 2 | |||
17. | ALA2059865 | 11f | inhibition | = | -0.2 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
18. | ALA2059865 | 11f | inhibition | = | 6.17 | % | ALA4808150 | % | Homo sapiens | |||
19. | ALA2059865 | 11f | inhibition | = | 21.3 | % | ALA4808149 | % | Homo sapiens | |||
20. | ALA2059865 | 11f | Inhibition | = | 18.19 | % | ALA4303805 | % | Severe acute respiratory syndrome coronavirus 2 |