# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Vapendavir | 6, BTA798 | pIC50 | < | 4.7 | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | |||
2. | Vapendavir | 6, BTA798 | IC50 | > | 0 | M | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
3. | Vapendavir | 6, BTA798 | Solubility | 2.9 | uM | ALA3301364 | nM | |||||
4. | Vapendavir | 6, BTA798 | PPB | 99.86 | % | ALA3301365 | % | |||||
5. | Vapendavir | 6, BTA798 | PPB | 99.85 | % | ALA3301366 | % | |||||
6. | Vapendavir | 6, BTA798 | PPB | 99.69 | % | ALA3301367 | % | |||||
7. | Vapendavir | 6, BTA798 | LogD7.4 | 4.23 | ALA3301363 | |||||||
8. | Vapendavir | 6, BTA798 | CLint | 30.2 | microL/min/mg | ALA3301370 | mL.min-1.g-1 | |||||
9. | Vapendavir | 6, BTA798 | CLint | 29.51 | microL/min/1E6 cells | ALA3301372 | uL.min-1.(10^6cells)-1 | |||||
10. | Vapendavir | 6, BTA798 | CLint | 8.13 | microL/min/1E6 cells | ALA3301371 | uL.min-1.(10^6cells)-1 | |||||
11. | Vapendavir | 6, BTA798 | CC50 | = | 721 | uM | ALA4012816 | nM | ||||
12. | Vapendavir | 6, BTA798 | Ratio EC50 | = | 792 | ALA4012815 | rhinovirus B14 | |||||
13. | Vapendavir | 6, BTA798 | Ratio EC50 | = | 6 | ALA4012814 | rhinovirus B14 | |||||
14. | Vapendavir | 6, BTA798 | EC50 | = | 24.208 | uM | ALA4012813 | 4.62 | nM | rhinovirus B14 | ||
15. | Vapendavir | 6, BTA798 | EC50 | = | 0.18 | uM | ALA4012812 | 6.75 | nM | rhinovirus B14 | ||
16. | Vapendavir | 6, BTA798 | EC50 | = | 0.031 | uM | ALA4012795 | 7.51 | nM | rhinovirus B14 | ||
17. | Vapendavir | 6, BTA798 | Activity | 0 | ALA2065746 | Non-toxic | Homo sapiens | |||||
18. | Vapendavir | 6, BTA798 | Activity | 0 | ALA2065745 | Non-toxic | Homo sapiens | |||||
19. | Vapendavir | 6, BTA798 | AUC | = | 13758 | ng.hr/ml | ALA2065744 | ng.hr.mL-1 | Homo sapiens | |||
20. | Vapendavir | 6, BTA798 | t1/2 | = | 11.8 | hr | ALA2065743 | hr | Homo sapiens |