| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  BMS-846372 | 5, BMS-846372 | Cp | = | 1500 | nM | ALA2065560 | nM | ||||
| 2. | BMS-846372 | 5, BMS-846372 | Cp | > | 1000 | nM | ALA2065559 | nM | ||||
| 3. | BMS-846372 | 5, BMS-846372 | t1/2 | = | 24 | min | ALA2065558 | hr | Homo sapiens | |||
| 4. | BMS-846372 | 5, BMS-846372 | Stability | = | 74 | % | ALA2065557 | % | Homo sapiens | |||
| 5. | BMS-846372 | 5, BMS-846372 | F | = | 38 | % | ALA2065556 | % | Macaca fascicularis | |||
| 6. | BMS-846372 | 5, BMS-846372 | F | = | 34 | % | ALA2065555 | % | Canis lupus familiaris | |||
| 7. | BMS-846372 | 5, BMS-846372 | F | = | 29 | % | ALA2065554 | % | Rattus norvegicus | |||
| 8. | BMS-846372 | 5, BMS-846372 | permeability | = | 880 | nm/s | ALA2065553 | nm/s | ||||
| 9. | BMS-846372 | 5, BMS-846372 | permeability | = | 1500 | nm/s | ALA2065552 | nm/s | ||||
| 10. | BMS-846372 | 5, BMS-846372 | IC50 | = | 0.22 | nM | ALA2065551 | 9.66 | nM | Homo sapiens | ||
| 11. | BMS-846372 | 5, BMS-846372 | Ki | = | 0.07 | nM | ALA2065550 | 10.15 | nM | Homo sapiens | ||
| 12. | BMS-846372 | 5, BMS-846372 | INH | = | 52 | % | ALA2065549 | % | marmosets | |||
| 13. | BMS-846372 | 5, BMS-846372 | INH | = | 52 | % | ALA2065548 | % | marmosets |
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