| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2063324 | 8d | IC50 | = | 0.01 | uM | ALA2390018 | 8.00 | nM | Homo sapiens | ||
| 2. | ALA2063324 | 8d | IC50 | = | 0.12 | uM | ALA2390017 | 6.92 | nM | Homo sapiens | ||
| 3. | ALA2063324 | 8d | IC50 | > | 1 | uM | ALA2390016 | nM | Homo sapiens | |||
| 4. | ALA2063324 | 8d | GI50 | = | 0.002 | uM | ALA2390015 | nM | Homo sapiens | |||
| 5. | ALA2063324 | 8d | IC50 | = | 1 | nM | ALA2066309 | 9.00 | nM | Homo sapiens | ||
| 6. | ALA2063324 | 8d | Activity | 0 | ALA2064919 | Non-toxic | Mus musculus | |||||
| 7. | ALA2063324 | 8d | Activity | 0 | ALA2064918 | Active | Homo sapiens | |||||
| 8. | ALA2063324 | 8d | Activity | 0 | ALA2064917 | Active | Homo sapiens | |||||
| 9. | ALA2063324 | 8d | F | = | 5 | % | ALA2064916 | % | Rattus norvegicus | |||
| 10. | ALA2063324 | 8d | t1/2 | = | 6.2 | hr | ALA2064915 | hr | Rattus norvegicus | |||
| 11. | ALA2063324 | 8d | CL | = | 16.2 | ml/min.kg | ALA2064914 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 12. | ALA2063324 | 8d | Vd | = | 6 | L/Kg | ALA2064913 | L.kg-1 | Rattus norvegicus | |||
| 13. | ALA2063324 | 8d | Cp | = | 17 | nM | ALA2064912 | nM | Rattus norvegicus | |||
| 14. | ALA2063324 | 8d | AUC | = | 5793 | nM.hr | ALA2066312 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 15. | ALA2063324 | 8d | Cmax | = | 5433 | nM | ALA2066311 | nM | Rattus norvegicus | |||
| 16. | ALA2063324 | 8d | AUC | = | 1380 | ng/mL.hr | ALA2066310 | ng.hr.mL-1 | Rattus norvegicus | |||
| 17. | ALA2063324 | 8d | INH | 0 | ALA2066309 | Dose-dependent effect | % | Homo sapiens | ||||
| 18. | ALA2063324 | 8d | GI50 | = | 3 | nM | ALA2066308 | nM | Homo sapiens | |||
| 19. | ALA2063324 | 8d | GI50 | = | 2 | nM | ALA2066307 | nM | Homo sapiens | |||
| 20. | ALA2063324 | 8d | IC50 | > | 1000 | nM | ALA2066306 | nM | Homo sapiens |
The page will load shortly, Thanks for your patience!