# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2069411 | 13 | Activity | 0 | ALA2073220 | Not Active | Homo sapiens | |||||
2. | ALA2069411 | 13 | Activity | 0 | ALA2073219 | Not Active | Homo sapiens | |||||
3. | ALA2069411 | 13 | IC50 | = | 0.2 | uM | ALA2072770 | 6.70 | nM | Homo sapiens | ||
4. | ALA2069411 | 13 | IC50 | = | 2 | uM | ALA2072769 | 5.70 | nM | Homo sapiens | ||
5. | ALA2069411 | 13 | INH | = | 98 | % | ALA2072768 | % | Homo sapiens | |||
6. | ALA2069411 | 13 | INH | = | 80 | % | ALA2072767 | % | Homo sapiens | |||
7. | ALA2069411 | 13 | INH | = | 55 | % | ALA2072766 | % | Homo sapiens | |||
8. | ALA2069411 | 13 | F | = | 66.3 | % | ALA2072765 | % | Rattus norvegicus | |||
9. | ALA2069411 | 13 | t1/2 | = | 3.5 | hr | ALA2072764 | hr | Rattus norvegicus | |||
10. | ALA2069411 | 13 | Tmax | = | 1.5 | hr | ALA2072763 | hr | Rattus norvegicus | |||
11. | ALA2069411 | 13 | Cmax | = | 0.38 | umol/L | ALA2072762 | nM | Rattus norvegicus | |||
12. | ALA2069411 | 13 | AUC/dose | = | 0.27 | hr.Kg/L | ALA2072761 | hr.Kg/L | Rattus norvegicus | |||
13. | ALA2069411 | 13 | CL | = | 42.2 | ml/min.kg | ALA2072760 | mL.min-1.kg-1 | Rattus norvegicus | |||
14. | ALA2069411 | 13 | t1/2 | = | 3.8 | hr | ALA2072759 | hr | Rattus norvegicus | |||
15. | ALA2069411 | 13 | Vdss | = | 11 | L/Kg | ALA2072758 | L.kg-1 | Rattus norvegicus | |||
16. | ALA2069411 | 13 | AUC/dose | = | 0.4 | hr.Kg/L | ALA2072757 | hr.Kg/L | Rattus norvegicus | |||
17. | ALA2069411 | 13 | Activity | 0 | ALA2072756 | Not Active | Homo sapiens | |||||
18. | ALA2069411 | 13 | CLH | = | 10 | uL/min/ug | ALA2072755 | mL.min-1.g-1 | Homo sapiens | |||
19. | ALA2069411 | 13 | CLH | < | 10 | uL/min/ug | ALA2072754 | mL.min-1.g-1 | Rattus norvegicus | |||
20. | ALA2069411 | 13 | solubility | = | 58 | uM | ALA2072753 | nM |