# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2086582 | 25, SEN15924, WAY-361789 | Activity | 0 | ALA2091654 | Not Active | Homo sapiens | |||||
2. | ALA2086582 | 25, SEN15924, WAY-361789 | Activity | 0 | ALA2091653 | Not Active | Homo sapiens | |||||
3. | ALA2086582 | 25, SEN15924, WAY-361789 | Activity | 0 | ALA2091652 | Not Active | Homo sapiens | |||||
4. | ALA2086582 | 25, SEN15924, WAY-361789 | MED | = | 10 | mg kg-1 | ALA2091651 | mg kg-1 | Rattus norvegicus | |||
5. | ALA2086582 | 25, SEN15924, WAY-361789 | Activity | 0 | ALA2091650 | Toxic | Rattus norvegicus | |||||
6. | ALA2086582 | 25, SEN15924, WAY-361789 | Activity | 0 | ALA2091649 | Active | Rattus norvegicus | |||||
7. | ALA2086582 | 25, SEN15924, WAY-361789 | Activity | 0 | ALA2091648 | Active | Rattus norvegicus | |||||
8. | ALA2086582 | 25, SEN15924, WAY-361789 | Activity | 0 | ALA2091647 | Not Active | Rattus norvegicus | |||||
9. | ALA2086582 | 25, SEN15924, WAY-361789 | MED | = | 1 | mg kg-1 | ALA2091646 | mg kg-1 | Rattus norvegicus | |||
10. | ALA2086582 | 25, SEN15924, WAY-361789 | Cmax | = | 3.7 | ng/g | ALA2091645 | ng/g | Rattus norvegicus | |||
11. | ALA2086582 | 25, SEN15924, WAY-361789 | BPR | = | 0.38 | ALA2091644 | ||||||
12. | ALA2086582 | 25, SEN15924, WAY-361789 | F | = | 12 | % | ALA2091643 | % | Rattus norvegicus | |||
13. | ALA2086582 | 25, SEN15924, WAY-361789 | AUC | = | 1.37 | uM.hr | ALA2091642 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
14. | ALA2086582 | 25, SEN15924, WAY-361789 | Tmax | = | 0.83 | hr | ALA2091641 | hr | Rattus norvegicus | |||
15. | ALA2086582 | 25, SEN15924, WAY-361789 | Cmax | = | 0.18 | uM | ALA2091640 | nM | Rattus norvegicus | |||
16. | ALA2086582 | 25, SEN15924, WAY-361789 | Ratio | = | 4.6 | ALA2091639 | Canis lupus familiaris | |||||
17. | ALA2086582 | 25, SEN15924, WAY-361789 | Papp | = | 1.6 | ucm/s | ALA2091638 | ucm/s | Canis lupus familiaris | |||
18. | ALA2086582 | 25, SEN15924, WAY-361789 | CLH | = | 13 | uL/min | ALA2091637 | uL/min | Rattus norvegicus | |||
19. | ALA2086582 | 25, SEN15924, WAY-361789 | Stability | = | 55 | % | ALA2091636 | % | Rattus norvegicus | |||
20. | ALA2086582 | 25, SEN15924, WAY-361789 | IC50 | = | 24.2 | uM | ALA2091635 | 4.62 | nM | Homo sapiens |