# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2087549 | 46, E2508 | IC50 | = | 16.3 | uM | ALA2089430 | 4.79 | nM | Homo sapiens | ||
2. | ALA2087549 | 46, E2508 | Activity | 0 | ALA2089429 | Not Active | Homo sapiens | |||||
3. | ALA2087549 | 46, E2508 | F | = | 31 | % | ALA2089428 | % | Mus musculus | |||
4. | ALA2087549 | 46, E2508 | AUC | = | 0.87 | ug/ml.hr | ALA2089427 | ng.hr.mL-1 | Mus musculus | |||
5. | ALA2087549 | 46, E2508 | Tmax | = | 0.25 | hr | ALA2089426 | hr | Mus musculus | |||
6. | ALA2087549 | 46, E2508 | Cmax | = | 0.32 | ug ml-1 | ALA2089425 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
7. | ALA2087549 | 46, E2508 | beta t1/2 | = | 2.2 | hr | ALA2089424 | hr | Mus musculus | |||
8. | ALA2087549 | 46, E2508 | AUC | = | 0.85 | ug/ml.hr | ALA2089423 | ng.hr.mL-1 | Mus musculus | |||
9. | ALA2087549 | 46, E2508 | Vdss | = | 3.74 | L/Kg | ALA2089422 | L.kg-1 | Mus musculus | |||
10. | ALA2087549 | 46, E2508 | CL | = | 2.6 | L/hr/kg | ALA2089421 | mL.min-1.kg-1 | Mus musculus | |||
11. | ALA2087549 | 46, E2508 | Activity | 0 | ALA2089420 | Active | Mus musculus | |||||
12. | ALA2087549 | 46, E2508 | Activity | 0 | ALA2089419 | Active | Mus musculus | |||||
13. | ALA2087549 | 46, E2508 | Ki | > | 10 | uM | ALA2089418 | nM | Homo sapiens | |||
14. | ALA2087549 | 46, E2508 | Ki | = | 11 | nM | ALA2089417 | 7.96 | nM | Homo sapiens |