# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | AL 8697 | 40 | INH | = | 67 | % | ALA2092523 | % | Rattus norvegicus | |||
2. | AL 8697 | 40 | ED50 | = | 1.36 | mg kg-1 | ALA2092522 | mg.kg-1 | Rattus norvegicus | |||
3. | AL 8697 | 40 | IC50 | = | 2 | uM | ALA2092477 | 5.70 | nM | Homo sapiens | ||
4. | AL 8697 | 40 | INH | 0 | ALA2092475 | Not Active | % | Homo sapiens | ||||
5. | AL 8697 | 40 | INH | 0 | ALA2092474 | Not Active | % | Homo sapiens | ||||
6. | AL 8697 | 40 | INH | 0 | ALA2092473 | Not Active | % | Homo sapiens | ||||
7. | AL 8697 | 40 | INH | 0 | ALA2092472 | Not Active | % | Homo sapiens | ||||
8. | AL 8697 | 40 | INH | 0 | ALA2092471 | Not Active | % | Homo sapiens | ||||
9. | AL 8697 | 40 | Activity | 0 | ALA2092470 | Non-toxic | Cricetulus griseus | |||||
10. | AL 8697 | 40 | t1/2 | = | 7.3 | hr | ALA2092469 | hr | Canis lupus familiaris | |||
11. | AL 8697 | 40 | F | = | 79 | % | ALA2092468 | % | Canis lupus familiaris | |||
12. | AL 8697 | 40 | AUC | = | 5055 | ng.hr/ml | ALA2092467 | ng.hr.mL-1 | Canis lupus familiaris | |||
13. | AL 8697 | 40 | Cmax | = | 185 | ug ml-1 | ALA2092466 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Canis lupus familiaris | ||
14. | AL 8697 | 40 | Vdss | = | 1.6 | L/Kg | ALA2092465 | L.kg-1 | Canis lupus familiaris | |||
15. | AL 8697 | 40 | CL | = | 2.7 | ml/min.kg | ALA2092464 | mL.min-1.kg-1 | Canis lupus familiaris | |||
16. | AL 8697 | 40 | AUC | = | 6438 | ng.hr/ml | ALA2092463 | ng.hr.mL-1 | Canis lupus familiaris | |||
17. | AL 8697 | 40 | F | = | 50 | % | ALA2092462 | % | Rattus norvegicus | |||
18. | AL 8697 | 40 | AUC | = | 38561 | ng.hr/ml | ALA2092461 | ng.hr.mL-1 | Rattus norvegicus | |||
19. | AL 8697 | 40 | Cmax | = | 3471 | ug ml-1 | ALA2092460 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
20. | AL 8697 | 40 | Vdss | = | 0.57 | L/Kg | ALA2092459 | L.kg-1 | Rattus norvegicus |