| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2088591 | 20 | INH | = | 52 | % | ALA2090356 | % | Rattus norvegicus | |||
| 2. | ALA2088591 | 20 | INH | = | 80 | % | ALA2090355 | % | Rattus norvegicus | |||
| 3. | ALA2088591 | 20 | F | = | 60 | % | ALA2090354 | % | Macaca mulatta | |||
| 4. | ALA2088591 | 20 | F | = | 87 | % | ALA2090353 | % | Canis lupus familiaris | |||
| 5. | ALA2088591 | 20 | F | = | 87 | % | ALA2090352 | % | Rattus norvegicus | |||
| 6. | ALA2088591 | 20 | AUC | = | 6.3 | uM.hr | ALA2090351 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Macaca mulatta | ||
| 7. | ALA2088591 | 20 | AUC | = | 7.6 | uM.hr | ALA2090350 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Canis lupus familiaris | ||
| 8. | ALA2088591 | 20 | AUC | = | 6.4 | uM.hr | ALA2090349 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 9. | ALA2088591 | 20 | CL | = | 3.4 | ml/min.kg | ALA2090348 | mL.min-1.kg-1 | Macaca mulatta | |||
| 10. | ALA2088591 | 20 | CL | = | 4.1 | ml/min.kg | ALA2090347 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 11. | ALA2088591 | 20 | CL | = | 4.9 | ml/min.kg | ALA2090346 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 12. | ALA2088591 | 20 | t1/2 | = | 3.8 | hr | ALA2090345 | hr | Macaca mulatta | |||
| 13. | ALA2088591 | 20 | t1/2 | = | 3 | hr | ALA2090344 | hr | Canis lupus familiaris | |||
| 14. | ALA2088591 | 20 | t1/2 | = | 1.4 | hr | ALA2090343 | hr | Rattus norvegicus | |||
| 15. | ALA2088591 | 20 | Ratio | = | 15 | ALA2090342 | ||||||
| 16. | ALA2088591 | 20 | IC50 | = | 5 | nM | ALA2090340 | 8.30 | nM | Homo sapiens | ||
| 17. | ALA2088591 | 20 | IC50 | = | 4.6 | nM | ALA2090339 | 8.34 | nM | Homo sapiens | ||
| 18. | ALA2088591 | 20 | Ratio IC50 | = | 25 | ALA2090338 | ||||||
| 19. | ALA2088591 | 20 | IC50 | = | 8.5 | nM | ALA2090337 | 8.07 | nM | Mus musculus | ||
| 20. | ALA2088591 | 20 | IC50 | = | 0.33 | nM | ALA2090336 | 9.48 | nM | Mus musculus |
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