Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA425	15	Potency		28.184	uM	ALA1794467		inconclusive	nM	Homo sapiens
2.	ALA425	15	Ratio	=	44		ALA3529280
3.	ALA425	15	Ratio	=	48		ALA3529281
4.	ALA425	15	Drug metabolism		0		ALA2187774		Active
5.	ALA425	15	IC50	>	40	uM	ALA3562141		inactive	nM
6.	ALA425	15	IC50	=	9.535	uM	ALA3562052	5.02	inactive	nM
7.	ALA425	15	Hepatotoxicity (mechanism)		0		ALA3137740
8.	ALA425	15	Hepatotoxicity (time to onset)		0		ALA3137739		3 weeks
9.	ALA425	15	Hepatotoxicity (comment)		0		ALA3137738		RC/SULFASALAZINE
10.	ALA425	15	Hepatotoxicity (successful reintroduction)		0		ALA3137737
11.	ALA425	15	Hepatotoxicity (animal toxicity known)		0		ALA3137736
12.	ALA425	15	Hepatotoxicity (benign tumour)	=	0		ALA3137735		references out of a total of 2
13.	ALA425	15	Hepatotoxicity (malignant tumour)	=	0		ALA3137734		references out of a total of 2
14.	ALA425	15	Hepatotoxicity (steatosis)	=	0		ALA3137733		references out of a total of 2
15.	ALA425	15	Hepatotoxicity (association with vascular disease)	=	0		ALA3137732		references out of a total of 2
16.	ALA425	15	Hepatotoxicity (granulomatous hepatitis)	=	0		ALA3137731		references out of a total of 2
17.	ALA425	15	Hepatotoxicity (cirrhosis)	=	0		ALA3137730		references out of a total of 2
18.	ALA425	15	Hepatotoxicity (chronic liver disease)	=	0		ALA3137729		references out of a total of 2
19.	ALA425	15	Hepatotoxicity (severe hepatitis)	=	0		ALA3137728		references out of a total of 2
20.	ALA425	15	Hepatotoxicity (choleostasis)	=	1		ALA3137727		references out of a total of 2