Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	MMAE	MMAE	IC50	=	1	nM	ALA5152800	9.00		nM	Homo sapiens
2.	MMAE	MMAE	IC50	=	1.1	nM	ALA5152799	8.96		nM	Homo sapiens
3.	MMAE	MMAE	IC50	=	0.62	nM	ALA5152798	9.21		nM	Homo sapiens
4.	MMAE	MMAE	IC50	=	0.55	nM	ALA5152797	9.26		nM	Homo sapiens
5.	MMAE	MMAE	IC50	=	0.71	nM	ALA5152796	9.15		nM	Homo sapiens
6.	MMAE	MMAE	IC50	=	0.79	nM	ALA5152795	9.10		nM	Homo sapiens
7.	MMAE	MMAE	Activity		0		ALA5152781		Toxic
8.	MMAE	MMAE	IC50	=	0.068	nM	ALA5151311	10.17		nM	Homo sapiens
9.	MMAE	MMAE	IC50	=	0.096	nM	ALA5151310	10.02		nM	Homo sapiens
10.	MMAE	MMAE	IC50	=	88.19	nM	ALA5151306	7.05		nM	Homo sapiens
11.	MMAE	MMAE	permeability	=	0.079	10'-6 cm/s	ALA4220926			10'-6 cm/s
12.	MMAE	MMAE	IC50	=	2.1	nM	ALA4220925	8.68		nM	Mus musculus
13.	MMAE	MMAE	IC50	=	1.3	nM	ALA4220924	8.89		nM	Homo sapiens
14.	MMAE	MMAE	IC50	=	0.66	nM	ALA4220923	9.18		nM	Homo sapiens
15.	MMAE	MMAE	GI50	=	0.22	nM	ALA3390352			nM	Homo sapiens
16.	MMAE	MMAE	GI50	=	0.54	nM	ALA3390354			nM	Homo sapiens
17.	MMAE	MMAE	GI50	=	0.49	nM	ALA3390353			nM	Homo sapiens
18.	MMAE	MMAE	CLH(app)	=	24	microL/min/mg	ALA3390355			mL.min-1.g-1	Homo sapiens
19.	MMAE	MMAE	CLH(app)	=	3	microL/min/mg	ALA3390356			mL.min-1.g-1	Homo sapiens
20.	MMAE	MMAE	GI50	>	1.39	nM	ALA4033913			nM	Homo sapiens