Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	MonoMethyl auristatin E	MMAE	IC50	=	0.19	nM	ALA2421238	9.72		nM	Homo sapiens
2.	MonoMethyl auristatin E	MMAE	IC50	=	0.59	nM	ALA2421239	9.23		nM	Homo sapiens
3.	MonoMethyl auristatin E	MMAE	IC50	=	0.25	nM	ALA2421237	9.60		nM	Homo sapiens
4.	MonoMethyl auristatin E	MMAE	Activity		0		ALA2421027		Active
5.	MonoMethyl auristatin E	MMAE	FC	=	1.5		ALA2421026				Mus musculus
6.	MonoMethyl auristatin E	MMAE	GI50	=	0.22	nM	ALA3390352			nM	Homo sapiens
7.	MonoMethyl auristatin E	MMAE	GI50	=	0.54	nM	ALA3390354			nM	Homo sapiens
8.	MonoMethyl auristatin E	MMAE	GI50	=	0.49	nM	ALA3390353			nM	Homo sapiens
9.	MonoMethyl auristatin E	MMAE	CLH(app)	=	24	microL/min/mg	ALA3390355			mL.min-1.g-1	Homo sapiens
10.	MonoMethyl auristatin E	MMAE	CLH(app)	=	3	microL/min/mg	ALA3390356			mL.min-1.g-1	Homo sapiens
11.	MonoMethyl auristatin E	MMAE	IC50	=	3.7	nM	ALA4481444	8.43		nM	Homo sapiens
12.	MonoMethyl auristatin E	MMAE	GI50	>	1.39	nM	ALA4033913			nM	Homo sapiens
13.	MonoMethyl auristatin E	MMAE	GI50	=	0.404	nM	ALA4033914			nM	Homo sapiens
14.	MonoMethyl auristatin E	MMAE	GI50	=	0.432	nM	ALA4033915			nM	Homo sapiens
15.	MonoMethyl auristatin E	MMAE	GI50	=	0.683	nM	ALA4033916			nM	Homo sapiens
16.	MonoMethyl auristatin E	MMAE	GI50	=	0.599	nM	ALA4033917			nM	Homo sapiens
17.	MonoMethyl auristatin E	MMAE	GI50	=	0.418	nM	ALA4033918			nM	Homo sapiens
18.	MonoMethyl auristatin E	MMAE	permeability	=	0.079	10'-6 cm/s	ALA4220926			10'-6 cm/s
19.	MonoMethyl auristatin E	MMAE	IC50	=	2.1	nM	ALA4220925	8.68		nM	Mus musculus
20.	MonoMethyl auristatin E	MMAE	IC50	=	1.3	nM	ALA4220924	8.89		nM	Homo sapiens