Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	Orvepitant	ORVEPITANT	ID50	=	0.09	mg kg-1	ALA2447329		mg.kg-1	Meriones unguiculatus
2.	Orvepitant	ORVEPITANT	ID50	=	0.09	mg kg-1	ALA2447096		mg.kg-1	Meriones unguiculatus
3.	Orvepitant	ORVEPITANT	ID50	=	0.11	mg kg-1	ALA2447330		mg.kg-1	Meriones unguiculatus
4.	Orvepitant	ORVEPITANT	ID50	=	0.11	mg kg-1	ALA2447094		mg.kg-1	Meriones unguiculatus
5.	Orvepitant	ORVEPITANT	Ki	=	0.94	uM	ALA2447079	6.03	nM	Homo sapiens
6.	Orvepitant	ORVEPITANT	BPR	=	1.2		ALA2447335
7.	Orvepitant	ORVEPITANT	Drug uptake	=	1.2	ng/g	ALA2447332		ng/g
8.	Orvepitant	ORVEPITANT	Vdss	=	2	L/Kg	ALA2447340		L.kg-1	Canis lupus familiaris
9.	Orvepitant	ORVEPITANT	Ki	=	2.27	uM	ALA2447077	5.64	nM	Homo sapiens
10.	Orvepitant	ORVEPITANT	t1/2	=	2.3	hr	ALA2447339		hr	Rattus norvegicus
11.	Orvepitant	ORVEPITANT	Ki	=	3.26	uM	ALA2447078	5.49	nM
12.	Orvepitant	ORVEPITANT	ID50	=	3.36	mg kg-1	ALA2447095		mg.kg-1	Meriones unguiculatus
13.	Orvepitant	ORVEPITANT	Vdss	=	3.7	L/Kg	ALA2447341		L.kg-1	Rattus norvegicus
14.	Orvepitant	ORVEPITANT	Ki	=	4.54	uM	ALA2447080	5.34	nM
15.	Orvepitant	ORVEPITANT	CL	=	6	ml/min.kg	ALA2447342		mL.min-1.kg-1	Canis lupus familiaris
16.	Orvepitant	ORVEPITANT	t1/2	=	6.1	hr	ALA2447338		hr	Canis lupus familiaris
17.	Orvepitant	ORVEPITANT	pKi	=	10.2		ALA2447345	10.20	nM	Homo sapiens
18.	Orvepitant	ORVEPITANT	pKb	=	10.3		ALA2447344			Homo sapiens
19.	Orvepitant	ORVEPITANT	pKi	=	10.4		ALA2447333	10.40	nM
20.	Orvepitant	ORVEPITANT	pKi	=	10.5		ALA2447334	10.50	nM	Meriones unguiculatus