# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | Tmax | = | 5 | min | ALA3992226 | hr | Rattus norvegicus | |||
2. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | INH | 0 | ALA3992225 | Dose-dependent effect | % | Canis lupus familiaris | ||||
3. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | Activity | = | 12 | % | ALA3992224 | % | Canis lupus familiaris | |||
4. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | Activity | = | 11 | % | ALA3992223 | % | Canis lupus familiaris | |||
5. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | Activity | = | 17 | % | ALA3992222 | % | Canis lupus familiaris | |||
6. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | Activity | = | 14 | % | ALA3992221 | % | Canis lupus familiaris | |||
7. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | Activity | = | 58 | % | ALA3992220 | % | Canis lupus familiaris | |||
8. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | Activity | = | 35 | % | ALA3992219 | % | Canis lupus familiaris | |||
9. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | Activity | = | 56 | % | ALA3992218 | % | Canis lupus familiaris | |||
10. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | Activity | = | 61 | % | ALA3992217 | % | Canis lupus familiaris | |||
11. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | Activity | 0 | ALA3992216 | Non-Toxic | Canis lupus familiaris | |||||
12. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | Activity | 0 | ALA3992190 | Non-Toxic | Canis lupus familiaris | |||||
13. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | Activity | 0 | ALA3992215 | Non-Toxic | Canis lupus familiaris | |||||
14. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | Activity | 0 | ALA3992214 | Non-Toxic | Canis lupus familiaris | |||||
15. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | NOAEL | > | 300 | mg kg-1 | ALA3992213 | mg kg-1 | Canis lupus familiaris | |||
16. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | NOAEL | = | 300 | mg kg-1 | ALA3992212 | mg kg-1 | Canis lupus familiaris | |||
17. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | AUC | = | 559.4 | hr.ng/ml | ALA3992211 | ng.hr.mL-1 | Canis lupus familiaris | |||
18. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | AUC | = | 256.6 | hr.ng/ml | ALA3992210 | ng.hr.mL-1 | Canis lupus familiaris | |||
19. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | AUC | = | 97.9 | hr.ng/ml | ALA3992209 | ng.hr.mL-1 | Canis lupus familiaris | |||
20. | ALA2105685 | AMUVATINIB HYDROCHLORIDE | Cmax | = | 192.4 | ng/ml | ALA3992208 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Canis lupus familiaris |