| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2105755 | NALDEMEDINE | Ratio ED50 | > | 500 | ALA4310633 | Rattus norvegicus | |||||
| 2. | ALA2105755 | NALDEMEDINE | Ratio ED50 | > | 1000 | ALA4310632 | ||||||
| 3. | ALA2105755 | NALDEMEDINE | ED50 | > | 30 | mg kg-1 | ALA4310631 | mg.kg-1 | Rattus norvegicus | |||
| 4. | ALA2105755 | NALDEMEDINE | ED50 | = | 0.03 | mg kg-1 | ALA4310629 | mg.kg-1 | Rattus norvegicus | |||
| 5. | ALA2105755 | NALDEMEDINE | ED50 | = | 0.03 | mg kg-1 | ALA4310627 | mg.kg-1 | Mustela putorius furo | |||
| 6. | ALA2105755 | NALDEMEDINE | Ke | = | 0.37 | nM | ALA4310626 | nM | Homo sapiens | |||
| 7. | ALA2105755 | NALDEMEDINE | Ke | = | 0.05 | nM | ALA4310625 | nM | Homo sapiens | |||
| 8. | ALA2105755 | NALDEMEDINE | Stability | > | 80 | % | ALA4310624 | % | ||||
| 9. | ALA2105755 | NALDEMEDINE | Stability | 0 | ALA4310623 | Stable | % | |||||
| 10. | ALA2105755 | NALDEMEDINE | Cmax | = | 1.3 | ng/ml | ALA4310621 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 11. | ALA2105755 | NALDEMEDINE | Kp | = | 0.03 | ALA4310620 | Rattus norvegicus | |||||
| 12. | ALA2105755 | NALDEMEDINE | F | = | 29 | % | ALA4310619 | % | ||||
| 13. | ALA2105755 | NALDEMEDINE | CL | = | 20 | ml/min.kg | ALA4310618 | mL.min-1.kg-1 | ||||
| 14. | ALA2105755 | NALDEMEDINE | Stability | = | 76 | % | ALA4310617 | % | ||||
| 15. | ALA2105755 | NALDEMEDINE | Stability | = | 73 | % | ALA4310616 | % | ||||
| 16. | ALA2105755 | NALDEMEDINE | Ki | = | 0.91 | nM | ALA4310615 | 9.04 | nM | Homo sapiens | ||
| 17. | ALA2105755 | NALDEMEDINE | Ki | = | 1.1 | nM | ALA4310614 | 8.96 | nM | Homo sapiens |
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