| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA314627 | 7, A-420983 | Inhibition | > | 90 | % | ALA698861 | % | Mus musculus | |||
| 2. | ALA314627 | 7, A-420983 | Inhibition | > | 90 | % | ALA698586 | % | Mus musculus | |||
| 3. | ALA314627 | 7, A-420983 | ED90 | = | 6 | mg kg-1 | ALA698860 | mg kg-1 | Mus musculus | |||
| 4. | ALA314627 | 7, A-420983 | ED50 | = | 1.5 | mg kg-1 | ALA698859 | mg.kg-1 | Mus musculus | |||
| 5. | ALA314627 | 7, A-420983 | F | = | 30 | % | ALA621687 | % | Canis lupus familiaris | |||
| 6. | ALA314627 | 7, A-420983 | T1/2 | = | 1.7 | hr | ALA618828 | hr | Canis lupus familiaris | |||
| 7. | ALA314627 | 7, A-420983 | Clp | = | 1.7 | l hr-1 kg-1 | ALA624543 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 8. | ALA314627 | 7, A-420983 | Vd | = | 25 | l kg-1 | ALA619552 | L.kg-1 | Canis lupus familiaris | |||
| 9. | ALA314627 | 7, A-420983 | T max | = | 8 | hr | ALA623681 | hr | Canis lupus familiaris | |||
| 10. | ALA314627 | 7, A-420983 | Cmax | = | 51 | ng ml-1 | ALA627878 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Canis lupus familiaris | ||
| 11. | ALA314627 | 7, A-420983 | F | = | 30 | % | ALA624341 | % | Mus musculus | |||
| 12. | ALA314627 | 7, A-420983 | T1/2 | = | 1.7 | hr | ALA627596 | hr | Mus musculus | |||
| 13. | ALA314627 | 7, A-420983 | Clp | = | 1.7 | l hr-1 kg-1 | ALA623504 | mL.min-1.kg-1 | Mus musculus | |||
| 14. | ALA314627 | 7, A-420983 | Vd | = | 25 | l kg-1 | ALA876724 | L.kg-1 | Mus musculus | |||
| 15. | ALA314627 | 7, A-420983 | T max | = | 8 | hr | ALA618949 | hr | Mus musculus | |||
| 16. | ALA314627 | 7, A-420983 | Cmax | = | 51 | ng ml-1 | ALA623413 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 17. | ALA314627 | 7, A-420983 | IC50 | = | 0.008 | uM | ALA819966 | 8.10 | nM | Homo sapiens | ||
| 18. | ALA314627 | 7, A-420983 | IC50 | = | 1.484 | uM | ALA814615 | 5.83 | nM | Homo sapiens | ||
| 19. | ALA314627 | 7, A-420983 | IC50 | > | 50 | uM | ALA816965 | nM | Homo sapiens | |||
| 20. | ALA314627 | 7, A-420983 | IC50 | = | 0.07 | uM | ALA806434 | 7.16 | nM | Homo sapiens |
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