# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2146873 | 30 | IC50 | = | 110 | nM | ALA3705830 | 6.96 | 311059 | nM | Homo sapiens | |
2. | ALA2146873 | 30 | IC50 | = | 170 | nM | ALA4004312 | 6.77 | nM | Homo sapiens | ||
3. | ALA2146873 | 30 | IC50 | = | 49 | nM | ALA4004311 | 7.31 | nM | Homo sapiens | ||
4. | ALA2146873 | 30 | IC50 | = | 0.055 | uM | ALA2148637 | 7.26 | nM | Rattus norvegicus | ||
5. | ALA2146873 | 30 | F | = | 64 | % | ALA2148636 | % | Rattus norvegicus | |||
6. | ALA2146873 | 30 | AUC/dose | = | 0.46 | uM.hr.kg/mg | ALA2148635 | uM.hr.kg/mg | Rattus norvegicus | |||
7. | ALA2146873 | 30 | t1/2 | = | 1.5 | hr | ALA2148634 | hr | Rattus norvegicus | |||
8. | ALA2146873 | 30 | CL | = | 59 | L/Kg | ALA2148633 | L/Kg | Rattus norvegicus | |||
9. | ALA2146873 | 30 | INH | < | 50 | % | ALA2148632 | % | Homo sapiens | |||
10. | ALA2146873 | 30 | INH | < | 50 | % | ALA2148631 | % | Homo sapiens | |||
11. | ALA2146873 | 30 | IC50 | = | 0.03 | uM | ALA2148630 | 7.52 | nM | Homo sapiens | ||
12. | ALA2146873 | 30 | IC50 | = | 0.17 | uM | ALA2148626 | 6.77 | nM | Homo sapiens | ||
13. | ALA2146873 | 30 | IC50 | = | 0.049 | uM | ALA2148625 | 7.31 | nM | Homo sapiens |