# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2146901 | 11b, CBt-PMN | solubility | = | 305 | uM | ALA4434138 | nM | ||||
2. | ALA2146901 | 11b, CBt-PMN | Emax | = | 75 | % | ALA4434137 | % | Homo sapiens | |||
3. | ALA2146901 | 11b, CBt-PMN | EC50 | = | 143 | nM | ALA4434136 | 6.84 | nM | Homo sapiens | ||
4. | ALA2146901 | 11b, CBt-PMN | Activity | = | 100 | % | ALA4434135 | % | ||||
5. | ALA2146901 | 11b, CBt-PMN | Activity | = | 44 | % | ALA4434134 | % | ||||
6. | ALA2146901 | 11b, CBt-PMN | Activity | = | 75 | % | ALA4434125 | % | ||||
7. | ALA2146901 | 11b, CBt-PMN | Activity | = | 82 | % | ALA4434127 | % | ||||
8. | ALA2146901 | 11b, CBt-PMN | Activity | = | 100 | % | ALA4434128 | % | ||||
9. | ALA2146901 | 11b, CBt-PMN | Survival | = | 100 | % | ALA4434129 | % | ||||
10. | ALA2146901 | 11b, CBt-PMN | Survival | = | 100 | % | ALA4434131 | % | ||||
11. | ALA2146901 | 11b, CBt-PMN | Survival | = | 100 | % | ALA4434132 | % | ||||
12. | ALA2146901 | 11b, CBt-PMN | Activity | = | 0 | % | ALA4434133 | % | ||||
13. | ALA2146901 | 11b, CBt-PMN | IC50 | = | 431.4 | nM | ALA5258392 | 6.37 | nM | Homo sapiens | ||
14. | ALA2146901 | 11b, CBt-PMN | -TdeltaS | = | -2.79 | kcal/mol | ALA5258391 | kcal/mol | Homo sapiens | |||
15. | ALA2146901 | 11b, CBt-PMN | deltaH | = | -6.08 | kcal/mol | ALA5258390 | kcal/mol | Homo sapiens | |||
16. | ALA2146901 | 11b, CBt-PMN | deltaG | = | -8.87 | kcal/mol | ALA5258389 | kcal/mol | Homo sapiens | |||
17. | ALA2146901 | 11b, CBt-PMN | Kd | = | 0.33 | uM | ALA5258388 | 6.48 | nM | Homo sapiens | ||
18. | ALA2146901 | 11b, CBt-PMN | -TdeltaS | = | -3.74 | kcal/mol | ALA5258387 | kcal/mol | Homo sapiens | |||
19. | ALA2146901 | 11b, CBt-PMN | -TdeltaS | = | -0.25 | kcal/mol | ALA5258386 | kcal/mol | Homo sapiens | |||
20. | ALA2146901 | 11b, CBt-PMN | deltaH | = | -5.21 | kcal/mol | ALA5258385 | kcal/mol | Homo sapiens |