| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2147088 | 7 | Activity | 0 | ALA2149085 | Non-toxic | Rattus norvegicus | |||||
| 2. | ALA2147088 | 7 | Activity | 0 | ALA2149084 | Non-toxic | Rattus norvegicus | |||||
| 3. | ALA2147088 | 7 | Activity | 0 | ALA2149083 | Non-toxic | Rattus norvegicus | |||||
| 4. | ALA2147088 | 7 | IC50 | = | 3.2 | ug ml-1 | ALA2149082 | ug.mL-1 | Chlorocebus sabaeus | |||
| 5. | ALA2147088 | 7 | F | = | 47.9 | % | ALA2149081 | % | Rattus norvegicus | |||
| 6. | ALA2147088 | 7 | Drugexcretion | = | 0.02 | % | ALA2149080 | % | ||||
| 7. | ALA2147088 | 7 | Vd | = | 2.86 | L/Kg | ALA2149079 | L.kg-1 | Rattus norvegicus | |||
| 8. | ALA2147088 | 7 | CL | = | 3.02 | L/hr/kg | ALA2149078 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 9. | ALA2147088 | 7 | t1/2 | = | 0.72 | hr | ALA2149077 | hr | Rattus norvegicus | |||
| 10. | ALA2147088 | 7 | AUC | = | 3.36 | mg.hr/L | ALA2149076 | ng.hr.mL-1 | Rattus norvegicus | |||
| 11. | ALA2147088 | 7 | Cmax | = | 2.73 | mg/L | ALA2149075 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 12. | ALA2147088 | 7 | Activity | = | 66.7 | % | ALA2149074 | % | Mycobacterium tuberculosis | |||
| 13. | ALA2147088 | 7 | Activity | = | 99.9 | % | ALA2149073 | % | Mycobacterium tuberculosis | |||
| 14. | ALA2147088 | 7 | Activity | 0 | ALA2149072 | Not Active | Pseudomonas aeruginosa | |||||
| 15. | ALA2147088 | 7 | Activity | 0 | ALA2149071 | Not Active | Stenotrophomonas maltophilia | |||||
| 16. | ALA2147088 | 7 | Activity | 0 | ALA2149070 | Not Active | Acinetobacter baumannii | |||||
| 17. | ALA2147088 | 7 | Activity | 0 | ALA2149069 | Not Active | Klebsiella pneumoniae | |||||
| 18. | ALA2147088 | 7 | Activity | 0 | ALA2148955 | Not Active | Proteus vulgaris | |||||
| 19. | ALA2147088 | 7 | Activity | 0 | ALA2148954 | Not Active | Proteus mirabilis | |||||
| 20. | ALA2147088 | 7 | Activity | 0 | ALA2148953 | Not Active | Burkholderia cepacia |
The page will load shortly, Thanks for your patience!