# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2147290 | 13, PF-02575799 | FC | = | 1 | ALA2149290 | Homo sapiens | |||||
2. | ALA2147290 | 13, PF-02575799 | Activity | = | 629 | % | ALA2149409 | % | Rattus norvegicus | |||
3. | ALA2147290 | 13, PF-02575799 | Activity | = | 111 | % | ALA2148816 | % | Rattus norvegicus | |||
4. | ALA2147290 | 13, PF-02575799 | Activity | = | 45 | % | ALA2149431 | % | Rattus norvegicus | |||
5. | ALA2147290 | 13, PF-02575799 | AUC | = | 51 | ng.hr/ml | ALA2149410 | ng.hr.mL-1 | Rattus norvegicus | |||
6. | ALA2147290 | 13, PF-02575799 | Activity | = | 25 | % | ALA2149424 | % | Rattus norvegicus | |||
7. | ALA2147290 | 13, PF-02575799 | Activity | = | 10 | % | ALA2149407 | % | Rattus norvegicus | |||
8. | ALA2147290 | 13, PF-02575799 | Activity | = | 16 | % | ALA2150034 | % | Rattus norvegicus | |||
9. | ALA2147290 | 13, PF-02575799 | Activity | = | 191 | % | ALA2149408 | % | Rattus norvegicus | |||
10. | ALA2147290 | 13, PF-02575799 | MED | = | 3 | mg kg-1 | ALA2149281 | mg kg-1 | Rattus norvegicus | |||
11. | ALA2147290 | 13, PF-02575799 | Activity | = | 152 | % | ALA2149430 | % | Rattus norvegicus | |||
12. | ALA2147290 | 13, PF-02575799 | AUC | = | 47 | ng.hr/ml | ALA2149411 | ng.hr.mL-1 | Rattus norvegicus | |||
13. | ALA2147290 | 13, PF-02575799 | Fu | = | 0.004 | ALA2150037 | ||||||
14. | ALA2147290 | 13, PF-02575799 | IC50 | = | 0.77 | nM | ALA2150039 | 9.11 | nM | Homo sapiens | ||
15. | ALA2147290 | 13, PF-02575799 | MED | = | 3 | mg kg-1 | ALA2149283 | mg kg-1 | Rattus norvegicus | |||
16. | ALA2147290 | 13, PF-02575799 | MED | = | 3 | mg kg-1 | ALA2149282 | mg kg-1 | Rattus norvegicus | |||
17. | ALA2147290 | 13, PF-02575799 | AUC | = | 170 | ng.hr/ml | ALA2149412 | ng.hr.mL-1 | Rattus norvegicus | |||
18. | ALA2147290 | 13, PF-02575799 | Activity | = | 56 | % | ALA2150035 | % | Rattus norvegicus | |||
19. | ALA2147290 | 13, PF-02575799 | Activity | = | 303 | % | ALA2149417 | % | Rattus norvegicus | |||
20. | ALA2147290 | 13, PF-02575799 | Activity | = | 28 | % | ALA2148814 | % | Rattus norvegicus |