# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2152523 | 2 | Drug metabolism | 0 | ALA4392951 | Metabolite_Detected | Homo sapiens | |||||
2. | ALA2152523 | 2 | IC50 | = | 0.41 | uM | ALA4392942 | 6.39 | nM | Homo sapiens | ||
3. | ALA2152523 | 2 | IC50 | > | 33 | uM | ALA4392943 | nM | Homo sapiens | |||
4. | ALA2152523 | 2 | IC50 | = | 1.4 | uM | ALA4392944 | 5.85 | nM | Homo sapiens | ||
5. | ALA2152523 | 2 | IC50 | = | 0.13 | uM | ALA4392945 | 6.89 | nM | Homo sapiens | ||
6. | ALA2152523 | 2 | logD | = | 4 | ALA4392946 | ||||||
7. | ALA2152523 | 2 | CLH | = | 14 | microL/min/mg | ALA4392947 | mL.min-1.g-1 | ||||
8. | ALA2152523 | 2 | Stability | 0 | ALA4392948 | Unstable | % | |||||
9. | ALA2152523 | 2 | PPB | 93.94 | % | ALA3301365 | % | |||||
10. | ALA2152523 | 2 | PPB | 83.68 | % | ALA3301367 | % | |||||
11. | ALA2152523 | 2 | CLint | 13.8 | microL/min/mg | ALA3301370 | mL.min-1.g-1 | |||||
12. | ALA2152523 | 2 | PPB | 74.69 | % | ALA3301368 | % | |||||
13. | ALA2152523 | 2 | CLint | 12.02 | microL/min/1E6 cells | ALA3301371 | uL.min-1.(10^6cells)-1 | |||||
14. | ALA2152523 | 2 | PPB | 63.47 | % | ALA3301366 | % | |||||
15. | ALA2152523 | 2 | PPB | 50 | % | ALA3301369 | % | |||||
16. | ALA2152523 | 2 | Vdss | = | 16.4 | L/Kg | ALA2153983 | L.kg-1 | Rattus norvegicus | |||
17. | ALA2152523 | 2 | t1/2 | = | 15.1 | hr | ALA2153982 | hr | Rattus norvegicus | |||
18. | ALA2152523 | 2 | CL | = | 13.1 | ml/min.kg | ALA2153981 | mL.min-1.kg-1 | Rattus norvegicus | |||
19. | ALA2152523 | 2 | F | = | 103.3 | % | ALA2153980 | % | Rattus norvegicus | |||
20. | ALA2152523 | 2 | Fu | = | 6.5 | % | ALA2153979 | Homo sapiens |