| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2153439 | 2c | PPB | 99.78 | % | ALA3301368 | % | |||||
| 2. | ALA2153439 | 2c | CLint | 60.26 | microL/min/1E6 cells | ALA3301372 | uL.min-1.(10^6cells)-1 | |||||
| 3. | ALA2153439 | 2c | IC50 | = | 30 | nM | ALA2156127 | 7.52 | nM | Homo sapiens | ||
| 4. | ALA2153439 | 2c | IC50 | = | 7 | nM | ALA2155423 | 8.15 | nM | Rattus norvegicus | ||
| 5. | ALA2153439 | 2c | Cp | = | 1.1 | uM | ALA2155434 | uM | Rattus norvegicus | |||
| 6. | ALA2153439 | 2c | Cp | = | 2 | uM | ALA2155433 | uM | Rattus norvegicus | |||
| 7. | ALA2153439 | 2c | Cp | = | 1.8 | uM | ALA2155432 | uM | Rattus norvegicus | |||
| 8. | ALA2153439 | 2c | AUC | = | 17.4 | uM.hr | ALA2155431 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 9. | ALA2153439 | 2c | Tmax | = | 1.8 | hr | ALA2155430 | hr | Rattus norvegicus | |||
| 10. | ALA2153439 | 2c | Cmax | = | 3.7 | uM | ALA2155429 | nM | Rattus norvegicus | |||
| 11. | ALA2153439 | 2c | beta t1/2 | = | 0.1 | hr | ALA2155428 | hr | Rattus norvegicus | |||
| 12. | ALA2153439 | 2c | Vdss | = | 0.5 | L/Kg | ALA2155427 | L.kg-1 | Rattus norvegicus | |||
| 13. | ALA2153439 | 2c | CL | = | 64.7 | ml/min.kg | ALA2155426 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 14. | ALA2153439 | 2c | Cmax | = | 19 | uM | ALA2155425 | nM | Rattus norvegicus | |||
| 15. | ALA2153439 | 2c | IC50 | > | 30 | uM | ALA2155424 | nM | Homo sapiens | |||
| 16. | ALA2153439 | 2c | PPB | = | 99 | % | ALA2155524 | % | Rattus norvegicus | |||
| 17. | ALA2153439 | 2c | Drug uptake | = | 7 | uM | ALA2155518 | uM | Rattus norvegicus | |||
| 18. | ALA2153439 | 2c | INH | = | 67 | % | ALA2155521 | % | Rattus norvegicus | |||
| 19. | ALA2153439 | 2c | INH | = | 71 | % | ALA2155520 | % | Rattus norvegicus | |||
| 20. | ALA2153439 | 2c | CLH | = | 1.2 | nmol/min/mg | ALA2155421 | nmol/min/mg | Rattus norvegicus |
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