# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2159512 | 2 | deltaTm | = | 7.8 | degrees C | ALA2161770 | degrees C | ||||
2. | ALA2159512 | 2 | IC50 | = | 57 | nM | ALA2161885 | 7.24 | nM | |||
3. | ALA2159512 | 2 | IC50 | > | 10000 | nM | ALA2161886 | nM | Homo sapiens | |||
4. | ALA2159512 | 2 | Ratio IC50 | > | 175 | ALA2161887 | ||||||
5. | ALA2159512 | 2 | EC50 | = | 415 | nM | ALA2161888 | 6.38 | nM | Trypanosoma brucei brucei | ||
6. | ALA2159512 | 2 | EC50 | = | 12000 | nM | ALA2161889 | 4.92 | nM | |||
7. | ALA2159512 | 2 | EC50 | = | 20000 | nM | ALA2161890 | 4.70 | nM | Homo sapiens | ||
8. | ALA2159512 | 2 | AQ | = | 0.21 | ALA2162449 | Homo sapiens | |||||
9. | ALA2159512 | 2 | Cp | = | 0.12 | uM | ALA2162448 | uM | Mus musculus | |||
10. | ALA2159512 | 2 | Drug uptake | = | 1.8 | uM | ALA2161893 | uM | Mus musculus | |||
11. | ALA2159512 | 2 | Papp | = | 455 | nm/s | ALA2161891 | nm/s | ||||
12. | ALA2159512 | 2 | Papp | = | 356 | nm/s | ALA2161892 | nm/s | ||||
13. | ALA2159512 | 2 | Cmax | = | 1.35 | uM | ALA2161894 | nM | Mus musculus | |||
14. | ALA2159512 | 2 | Tmax | = | 30 | min | ALA2162442 | hr | Mus musculus | |||
15. | ALA2159512 | 2 | t1/2 | = | 65 | min | ALA2162443 | hr | Mus musculus | |||
16. | ALA2159512 | 2 | AUC | = | 152 | uM.min | ALA2162444 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus |