# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2165367 | 14 | Activity | 0 | ALA3369487 | Toxic | Mus musculus | |||||
2. | ALA2165367 | 14 | Activity | 0 | ALA3369485 | Toxic | Mus musculus | |||||
3. | ALA2165367 | 14 | Activity | 0 | ALA3369486 | Toxic | Mus musculus | |||||
4. | ALA2165367 | 14 | AUC | = | 200 | hr.ng/ml | ALA2168966 | ng.hr.mL-1 | Mus musculus | |||
5. | ALA2165367 | 14 | F | = | 67.3 | % | ALA2168974 | % | Mus musculus | |||
6. | ALA2165367 | 14 | AUC | = | 269.1 | hr.ng/ml | ALA2168967 | ng.hr.mL-1 | Mus musculus | |||
7. | ALA2165367 | 14 | Tmax | = | 0.25 | hr | ALA2168964 | hr | Mus musculus | |||
8. | ALA2165367 | 14 | MRT | = | 0.6 | hr | ALA2168972 | hr | Mus musculus | |||
9. | ALA2165367 | 14 | MRT | = | 2.2 | hr | ALA2168973 | hr | Mus musculus | |||
10. | ALA2165367 | 14 | t1/2 | = | 2.9 | hr | ALA2168970 | hr | Mus musculus | |||
11. | ALA2165367 | 14 | t1/2 | = | 2.9 | hr | ALA2168971 | hr | Mus musculus | |||
12. | ALA2165367 | 14 | CL | = | 2.5 | L/hr/kg | ALA2168968 | mL.min-1.kg-1 | Mus musculus | |||
13. | ALA2165367 | 14 | Vdss | = | 1.6 | L/Kg | ALA2168969 | L.kg-1 | Mus musculus | |||
14. | ALA2165367 | 14 | IC50 | = | 5.9 | ng/ml | ALA2168745 | ug.mL-1 | ||||
15. | ALA2165367 | 14 | IC50 | = | 31 | ng/ml | ALA2168746 | ug.mL-1 | ||||
16. | ALA2165367 | 14 | Cmax | = | 254.5 | ng/ml | ALA2168965 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
17. | ALA2165367 | 14 | IC50 | = | 5 | nM | ALA2168744 | 8.30 | nM | Mus musculus | ||
18. | ALA2165367 | 14 | Activity | 0 | ALA2168955 | Active | ||||||
19. | ALA2165367 | 14 | Activity | 0 | ALA2168956 | Active | ||||||
20. | ALA2165367 | 14 | Activity | 0 | ALA2168958 | Active |