# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | PF 04991532 | 19 | EC50 | = | 90 | nM | ALA2168593 | 7.05 | nM | Homo sapiens | ||
2. | PF 04991532 | 19 | CLH | < | 8 | ml/min.kg | ALA2168594 | mL.min-1.kg-1 | Homo sapiens | |||
3. | PF 04991532 | 19 | Papp | = | 1 | ucm/s | ALA2168595 | ucm/s | ||||
4. | PF 04991532 | 19 | EC50 | = | 6900 | nM | ALA2168596 | 5.16 | nM | Rattus norvegicus | ||
5. | PF 04991532 | 19 | Ratio EC50 | = | 77 | ALA2168597 | Rattus norvegicus | |||||
6. | PF 04991532 | 19 | FC | > | 2 | ALA2168598 | Homo sapiens | |||||
7. | PF 04991532 | 19 | FC | > | 2 | ALA2168786 | Homo sapiens | |||||
8. | PF 04991532 | 19 | Kinetic_solubility | = | 524 | uM | ALA2168787 | nM | ||||
9. | PF 04991532 | 19 | Fu | = | 0.1 | ALA2168788 | Rattus norvegicus | |||||
10. | PF 04991532 | 19 | Fu | = | 0.17 | ALA2168789 | Canis lupus familiaris | |||||
11. | PF 04991532 | 19 | Fu | = | 0.11 | ALA2168790 | Macaca mulatta | |||||
12. | PF 04991532 | 19 | Fu | = | 0.13 | ALA2168791 | Homo sapiens | |||||
13. | PF 04991532 | 19 | Fu | = | 0.07 | ALA2168792 | Rattus norvegicus | |||||
14. | PF 04991532 | 19 | Fu | = | 0.09 | ALA2168793 | Canis lupus familiaris | |||||
15. | PF 04991532 | 19 | Fu | = | 0.11 | ALA2168794 | Rattus norvegicus | |||||
16. | PF 04991532 | 19 | Fu | = | 0.21 | ALA2168795 | ||||||
17. | PF 04991532 | 19 | Fu | = | 0.09 | ALA2168796 | Rattus norvegicus | |||||
18. | PF 04991532 | 19 | Fu | = | 0.13 | ALA2168797 | Canis lupus familiaris | |||||
19. | PF 04991532 | 19 | fAUC | = | 34.7 | ng.hr/ml | ALA2168798 | ng.hr.mL-1 | Rattus norvegicus | |||
20. | PF 04991532 | 19 | fAUC | = | 30.3 | ng.hr/ml | ALA2168799 | ng.hr.mL-1 | Rattus norvegicus |