Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA2170837	30, BM-957	LogD7.4		4.2		ALA3301363
2.	ALA2170837	30, BM-957	CLint		17.38	microL/min/1E6 cells	ALA3301371			uL.min-1.(10^6cells)-1
3.	ALA2170837	30, BM-957	CLint		15.14	microL/min/mg	ALA3301370			mL.min-1.g-1
4.	ALA2170837	30, BM-957	IC50	=	5.4	nM	ALA2173962	8.27		nM	Homo sapiens
5.	ALA2170837	30, BM-957	Ki	=	1.2	nM	ALA2173961	8.92		nM	Homo sapiens
6.	ALA2170837	30, BM-957	IC50	=	6	nM	ALA2173960	8.22		nM
7.	ALA2170837	30, BM-957	Ki	<	1	nM	ALA2173959			nM
8.	ALA2170837	30, BM-957	Activity		0		ALA2173958		Not Active		Homo sapiens
9.	ALA2170837	30, BM-957	IC50	=	21	nM	ALA2173957	7.68		nM	Homo sapiens
10.	ALA2170837	30, BM-957	IC50	=	22	nM	ALA2173956	7.66		nM
11.	ALA2170837	30, BM-957	Activity		0		ALA2173955		Dose-dependent effect		Homo sapiens
12.	ALA2170837	30, BM-957	Activity	>	50	%	ALA2173954			%	Homo sapiens
13.	ALA2170837	30, BM-957	Activity		0		ALA2173952		Active		Homo sapiens
14.	ALA2170837	30, BM-957	Activity		0		ALA2173951		Active		Homo sapiens
15.	ALA2170837	30, BM-957	MTD	=	25	mg kg-1	ALA2173950			mg kg-1	Mus musculus
16.	ALA2170837	30, BM-957	Activity	<	10	%	ALA2173948			%	Mus musculus
17.	ALA2170837	30, BM-957	Activity	>	10	%	ALA2173947			%	Mus musculus
18.	ALA2170837	30, BM-957	Activity		0		ALA2173870		Active		Homo sapiens
19.	ALA2170837	30, BM-957	Activity		0		ALA2173869		Active		Homo sapiens
20.	ALA2170837	30, BM-957	Activity		0		ALA2173866		Active