# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2172212 | 3, AM6-36 | IC50 | = | 12000 | nM | ALA3706179 | 4.92 | 275705 | nM | Homo sapiens | |
2. | ALA2172212 | 3, AM6-36 | Survival | = | 58.6 | % | ALA2175535 | % | Chlorocebus aethiops | |||
3. | ALA2172212 | 3, AM6-36 | PPB | = | 75 | % | ALA2175646 | % | Homo sapiens | |||
4. | ALA2172212 | 3, AM6-36 | INH | = | 84.9 | % | ALA2175529 | % | ||||
5. | ALA2172212 | 3, AM6-36 | Survival | = | 108.7 | % | ALA2175066 | % | Homo sapiens | |||
6. | ALA2172212 | 3, AM6-36 | Drug metabolism | = | 0.3 | ug/g | ALA2175648 | ug/g | ||||
7. | ALA2172212 | 3, AM6-36 | Drug metabolism | = | 4.3 | ug/g | ALA2175647 | ug/g | Rattus norvegicus | |||
8. | ALA2172212 | 3, AM6-36 | Drug metabolism | = | 0.8 | ug ml-1 | ALA2175666 | ug ml-1 | Rattus norvegicus | |||
9. | ALA2172212 | 3, AM6-36 | EC50 | = | 3.37 | uM | ALA2175533 | 5.47 | nM | Homo sapiens | ||
10. | ALA2172212 | 3, AM6-36 | IC50 | = | 26.3 | uM | ALA2175528 | 4.58 | nM | |||
11. | ALA2172212 | 3, AM6-36 | t1/2 | = | 130 | min | ALA2175653 | hr | Homo sapiens | |||
12. | ALA2172212 | 3, AM6-36 | CLH | = | 5.33 | ml/min.kg | ALA2175652 | mL.min-1.kg-1 | Homo sapiens | |||
13. | ALA2172212 | 3, AM6-36 | Kel | = | 0.005 | ALA2175654 | Homo sapiens | |||||
14. | ALA2172212 | 3, AM6-36 | FC | = | 0.35 | ALA2175642 | Homo sapiens | |||||
15. | ALA2172212 | 3, AM6-36 | FC | = | 2 | ALA2175530 | Homo sapiens | |||||
16. | ALA2172212 | 3, AM6-36 | FC | = | 5 | ALA2175531 | Homo sapiens | |||||
17. | ALA2172212 | 3, AM6-36 | FC | = | 7.67 | ALA2175537 | Homo sapiens | |||||
18. | ALA2172212 | 3, AM6-36 | FC | = | 40.5 | ALA2175534 | Homo sapiens | |||||
19. | ALA2172212 | 3, AM6-36 | FC | = | 160 | ALA2175532 | Homo sapiens | |||||
20. | ALA2172212 | 3, AM6-36 | Drug metabolism | 0 | ALA2175664 | Active | Homo sapiens |