# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2172315 | 49 | AUC | = | 0.957 | uM.hr | ALA3537089 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
2. | ALA2172315 | 49 | CL | = | 3.51 | l/hr.kg | ALA3537090 | mL.min-1.kg-1 | Mus musculus | |||
3. | ALA2172315 | 49 | MRT | = | 1.28 | hr | ALA3537091 | hr | Mus musculus | |||
4. | ALA2172315 | 49 | t1/2 | = | 1.01 | hr | ALA3537092 | hr | Mus musculus | |||
5. | ALA2172315 | 49 | Vdss | = | 4.49 | L/Kg | ALA3537093 | L.kg-1 | Mus musculus | |||
6. | ALA2172315 | 49 | t1/2 | = | 2.9 | hr | ALA3539377 | hr | Mus musculus | |||
7. | ALA2172315 | 49 | Vmax(app) | = | 3.81 | pmol/min.ml | ALA3541470 | pmol/min.ml | Mus musculus | |||
8. | ALA2172315 | 49 | Km(app) | = | 0.357 | uM | ALA3541470 | nM | Mus musculus | |||
9. | ALA2172315 | 49 | Vmax(app) | = | 5.12 | pmol/min.mg | ALA3541471 | pmol/min.mg | ||||
10. | ALA2172315 | 49 | Km(app) | = | 0.029 | uM | ALA3541471 | nM | ||||
11. | ALA2172315 | 49 | Vmax(app) | = | 143 | pmol/min.mg | ALA3541472 | pmol/min.mg | ||||
12. | ALA2172315 | 49 | Km(app) | = | 0.936 | uM | ALA3541472 | nM | ||||
13. | ALA2172315 | 49 | CL | = | 10.7 | uL/min.ml | ALA3541473 | uL/min.ml | Mus musculus | |||
14. | ALA2172315 | 49 | CLH | = | 175 | uL/min.mg | ALA3541474 | mL.min-1.g-1 | ||||
15. | ALA2172315 | 49 | CLH | = | 153 | uL/min.mg | ALA3541475 | mL.min-1.g-1 | ||||
16. | ALA2172315 | 49 | Ratio | = | 0.9 | ALA3541476 | ||||||
17. | ALA2172315 | 49 | Fu | = | 0.53 | ALA3541477 | Mus musculus | |||||
18. | ALA2172315 | 49 | Fu | = | 0.046 | ALA3541478 | Mus musculus | |||||
19. | ALA2172315 | 49 | CL | = | 3.51 | l/hr.kg | ALA3541479 | mL.min-1.kg-1 | Mus musculus | |||
20. | ALA2172315 | 49 | IC50 | = | 1 | nM | ALA4378233 | 9.00 | nM | Homo sapiens |