| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2177157 | 14 | Solubility | 2.7 | uM | ALA3301364 | nM | |||||
| 2. | ALA2177157 | 14 | LogD7.4 | 2.66 | ALA3301363 | |||||||
| 3. | ALA2177157 | 14 | Ki | = | 9 | nM | ALA2182637 | 8.05 | nM | Homo sapiens | ||
| 4. | ALA2177157 | 14 | Ki | = | 1400 | nM | ALA2182638 | 5.85 | nM | Homo sapiens | ||
| 5. | ALA2177157 | 14 | Ratio Ki | = | 155 | ALA2182246 | ||||||
| 6. | ALA2177157 | 14 | Therm_solubility | = | 108 | uM | ALA2182245 | nM | ||||
| 7. | ALA2177157 | 14 | Papp | = | 11 | ucm/s | ALA2182244 | ucm/s | Homo sapiens | |||
| 8. | ALA2177157 | 14 | IC50 | = | 49 | nM | ALA2182243 | 7.31 | nM | Mus musculus | ||
| 9. | ALA2177157 | 14 | pBBB | = | 3.9 | 10'-3cm/min | ALA2182242 | 10'-3cm/min | ||||
| 10. | ALA2177157 | 14 | INH | 0 | ALA2182243 | Dose-dependent effect | % | Mus musculus |
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