Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	AZD8329	27, AZD-8329	IC50	=	0.009	uM	ALA2184996	8.05	nM	Homo sapiens
2.	AZD8329	27, AZD-8329	logD	=	1		ALA2184995
3.	AZD8329	27, AZD-8329	Fu	=	1.3	%	ALA2184994			Rattus norvegicus
4.	AZD8329	27, AZD-8329	CLH	<	2	uL/min	ALA2184993		uL/min	Rattus norvegicus
5.	AZD8329	27, AZD-8329	CL	=	0.6	ml/min.kg	ALA2184989		mL.min-1.kg-1	Rattus norvegicus
6.	AZD8329	27, AZD-8329	F	=	95	%	ALA2184990		%	Rattus norvegicus
7.	AZD8329	27, AZD-8329	INH	<	25	%	ALA2184988		%	Homo sapiens
8.	AZD8329	27, AZD-8329	INH	<	25	%	ALA2184985		%	Homo sapiens
9.	AZD8329	27, AZD-8329	INH	<	25	%	ALA2184986		%	Homo sapiens
10.	AZD8329	27, AZD-8329	INH	<	25	%	ALA2184987		%	Homo sapiens
11.	AZD8329	27, AZD-8329	INH	<	25	%	ALA2184991		%	Homo sapiens
12.	AZD8329	27, AZD-8329	solubility	>	1900	uM	ALA2184992		nM
13.	AZD8329	27, AZD-8329	Fu	=	3.5	%	ALA2184983			Mus musculus
14.	AZD8329	27, AZD-8329	Fu	=	2	%	ALA2184984			Canis lupus familiaris
15.	AZD8329	27, AZD-8329	Fu	=	1.4	%	ALA2184981			Homo sapiens
16.	AZD8329	27, AZD-8329	Papp	=	7.3	ucm/s	ALA2184982		ucm/s	Canis lupus familiaris
17.	AZD8329	27, AZD-8329	Papp	=	3.9	ucm/s	ALA2184980		ucm/s	Canis lupus familiaris
18.	AZD8329	27, AZD-8329	Ratio	=	0.5		ALA2184979			Canis lupus familiaris
19.	AZD8329	27, AZD-8329	CL	=	9	ml/min.kg	ALA2184077		mL.min-1.kg-1	Mus musculus
20.	AZD8329	27, AZD-8329	CL	=	0.6	ml/min.kg	ALA2184978		mL.min-1.kg-1	Rattus norvegicus