| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2177914 | (S)-16 | IC50 | = | 36.2 | nM | ALA2183079 | 7.44 | nM | Homo sapiens | ||
| 2. | ALA2177914 | (S)-16 | IC50 | = | 8.64 | nM | ALA2183078 | 8.06 | nM | Homo sapiens | ||
| 3. | ALA2177914 | (S)-16 | Papp | = | 37 | ucm/s | ALA2182708 | ucm/s | Homo sapiens | |||
| 4. | ALA2177914 | (S)-16 | Ratio | = | 0.9 | ALA2182707 | Homo sapiens | |||||
| 5. | ALA2177914 | (S)-16 | IC50 | = | 19 | uM | ALA2182706 | 4.72 | nM | Homo sapiens | ||
| 6. | ALA2177914 | (S)-16 | CLH | = | 40.4 | uL/min | ALA2182705 | uL/min | Rattus norvegicus | |||
| 7. | ALA2177914 | (S)-16 | pKa | = | 6.2 | ALA2182704 | ||||||
| 8. | ALA2177914 | (S)-16 | logD | = | 2.3 | ALA2182702 | ||||||
| 9. | ALA2177914 | (S)-16 | Ratio IC50 | = | 2200 | ALA2182703 | ||||||
| 10. | ALA2177914 | (S)-16 | INH | 0 | ALA2182699 | Not Active | % | |||||
| 11. | ALA2177914 | (S)-16 | Ki | = | 770 | nM | ALA2182698 | 6.11 | nM | Homo sapiens | ||
| 12. | ALA2177914 | (S)-16 | IC50 | = | 53 | nM | ALA2187563 | 7.28 | nM | Mus musculus | ||
| 13. | ALA2177914 | (S)-16 | Activity | = | 40 | % | ALA2187560 | % | Mus musculus | |||
| 14. | ALA2177914 | (S)-16 | Fu | = | 11 | % | ALA2187555 | Mus musculus | ||||
| 15. | ALA2177914 | (S)-16 | Fu | = | 4.6 | % | ALA2187548 | Mus musculus | ||||
| 16. | ALA2177914 | (S)-16 | Activity | 0 | ALA2187540 | Active | Mus musculus | |||||
| 17. | ALA2177914 | (S)-16 | Activity | 0 | ALA2187534 | Active | Mus musculus | |||||
| 18. | ALA2177914 | (S)-16 | Cp(f) | = | 883 | nM | ALA2187119 | nM | Mus musculus | |||
| 19. | ALA2177914 | (S)-16 | Drug uptake(free) | = | 73 | nM | ALA2187113 | nM | Mus musculus |
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