# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2177917 | 35 | PPB | 96.57 | % | ALA3301365 | % | |||||
2. | ALA2177917 | 35 | PPB | 90.32 | % | ALA3301368 | % | |||||
3. | ALA2177917 | 35 | IC50 | = | 78.5 | nM | ALA2183079 | 7.11 | nM | Homo sapiens | ||
4. | ALA2177917 | 35 | IC50 | = | 2.92 | nM | ALA2183078 | 8.54 | nM | Homo sapiens | ||
5. | ALA2177917 | 35 | Papp | = | 33 | ucm/s | ALA2182708 | ucm/s | Homo sapiens | |||
6. | ALA2177917 | 35 | Ratio | = | 0.5 | ALA2182707 | Homo sapiens | |||||
7. | ALA2177917 | 35 | IC50 | = | 3.8 | uM | ALA2182706 | 5.42 | nM | Homo sapiens | ||
8. | ALA2177917 | 35 | CLH | = | 25.3 | uL/min | ALA2182705 | uL/min | Rattus norvegicus | |||
9. | ALA2177917 | 35 | pKa | = | 8.1 | ALA2182704 | ||||||
10. | ALA2177917 | 35 | logD | = | 2.7 | ALA2182702 | ||||||
11. | ALA2177917 | 35 | INH | 0 | ALA2182699 | Not Active | % | |||||
12. | ALA2177917 | 35 | Ki | = | 1700 | nM | ALA2182698 | 5.77 | nM | Homo sapiens | ||
13. | ALA2177917 | 35 | IC50 | = | 40 | nM | ALA2187563 | 7.40 | nM | Mus musculus | ||
14. | ALA2177917 | 35 | Activity | = | 50 | % | ALA2187559 | % | Mus musculus | |||
15. | ALA2177917 | 35 | Fu | = | 9.6 | % | ALA2187553 | Mus musculus | ||||
16. | ALA2177917 | 35 | Fu | = | 1.1 | % | ALA2187547 | Mus musculus | ||||
17. | ALA2177917 | 35 | Activity | 0 | ALA2187539 | Active | Mus musculus | |||||
18. | ALA2177917 | 35 | Activity | 0 | ALA2187533 | Active | Mus musculus | |||||
19. | ALA2177917 | 35 | Cp(f) | = | 237 | nM | ALA2187118 | nM | Mus musculus | |||
20. | ALA2177917 | 35 | Drug uptake(free) | = | 13 | nM | ALA2187112 | nM | Mus musculus |