# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2179277 | (R,S)-14, TK-666 | LogD7.4 | 1.09 | ALA3301363 | |||||||
2. | ALA2179277 | (R,S)-14, TK-666 | PPB | 98.51 | % | ALA3301366 | % | |||||
3. | ALA2179277 | (R,S)-14, TK-666 | PPB | 97.32 | % | ALA3301367 | % | |||||
4. | ALA2179277 | (R,S)-14, TK-666 | PPB | 97.13 | % | ALA3301365 | % | |||||
5. | ALA2179277 | (R,S)-14, TK-666 | CLint | 48.98 | microL/min/1E6 cells | ALA3301371 | uL.min-1.(10^6cells)-1 | |||||
6. | ALA2179277 | (R,S)-14, TK-666 | MIC | > | 64 | ug ml-1 | ALA3300456 | ug.mL-1 | Homo sapiens | |||
7. | ALA2179277 | (R,S)-14, TK-666 | Ratio IC50 | > | 25000 | ALA3300450 | ||||||
8. | ALA2179277 | (R,S)-14, TK-666 | MIC | = | 62000 | ug ml-1 | ALA3300449 | ug.mL-1 | Homo sapiens | |||
9. | ALA2179277 | (R,S)-14, TK-666 | MIC | > | 64 | ug ml-1 | ALA3300448 | ug.mL-1 | Pseudomonas aeruginosa | |||
10. | ALA2179277 | (R,S)-14, TK-666 | MIC | > | 64 | ug ml-1 | ALA3300447 | ug.mL-1 | Escherichia coli | |||
11. | ALA2179277 | (R,S)-14, TK-666 | MIC | = | 1 | ug ml-1 | ALA3300446 | ug.mL-1 | Enterococcus faecalis | |||
12. | ALA2179277 | (R,S)-14, TK-666 | MIC | = | 0.25 | ug ml-1 | ALA3300445 | ug.mL-1 | Enterococcus faecium | |||
13. | ALA2179277 | (R,S)-14, TK-666 | MIC | = | 2 | ug ml-1 | ALA3300444 | ug.mL-1 | Staphylococcus epidermidis | |||
14. | ALA2179277 | (R,S)-14, TK-666 | MIC90 | = | 0.5 | ug ml-1 | ALA3300443 | ug.mL-1 | Streptococcus pyogenes | |||
15. | ALA2179277 | (R,S)-14, TK-666 | MIC90 | = | 0.03 | ug ml-1 | ALA3300185 | ug.mL-1 | Streptococcus pneumoniae | |||
16. | ALA2179277 | (R,S)-14, TK-666 | CL | = | 42 | ml/min.kg | ALA3300184 | mL.min-1.kg-1 | Rattus norvegicus | |||
17. | ALA2179277 | (R,S)-14, TK-666 | Fu | < | 0.3 | % | ALA3300183 | Mus musculus | ||||
18. | ALA2179277 | (R,S)-14, TK-666 | Fu | = | 3.2 | % | ALA3300182 | Homo sapiens | ||||
19. | ALA2179277 | (R,S)-14, TK-666 | MIC90 | = | 1 | ug ml-1 | ALA3300180 | ug.mL-1 | Staphylococcus aureus | |||
20. | ALA2179277 | (R,S)-14, TK-666 | MIC90 | = | 1 | ug ml-1 | ALA3300179 | ug.mL-1 | Staphylococcus aureus |