| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2180410 | Figure 27, R1C3 | Drug uptake | = | 1212 | ng/g | ALA3396653 | ng/g | Rattus norvegicus | |||
| 2. | ALA2180410 | Figure 27, R1C3 | beta t1/2 | = | 0.8 | hr | ALA3396652 | hr | Rattus norvegicus | |||
| 3. | ALA2180410 | Figure 27, R1C3 | Vd | = | 1.9 | L/Kg | ALA3396651 | L.kg-1 | Rattus norvegicus | |||
| 4. | ALA2180410 | Figure 27, R1C3 | CL | = | 34 | ml/min.kg | ALA3396650 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 5. | ALA2180410 | Figure 27, R1C3 | F | = | 45 | % | ALA3396649 | % | Rattus norvegicus | |||
| 6. | ALA2180410 | Figure 27, R1C3 | PB | = | 85 | % | ALA3396648 | % | Rattus norvegicus | |||
| 7. | ALA2180410 | Figure 27, R1C3 | PB | = | 69 | % | ALA3396647 | % | Homo sapiens | |||
| 8. | ALA2180410 | Figure 27, R1C3 | PPB | = | 60 | % | ALA3396646 | % | Rattus norvegicus | |||
| 9. | ALA2180410 | Figure 27, R1C3 | PPB | = | 58 | % | ALA3396645 | % | Homo sapiens | |||
| 10. | ALA2180410 | Figure 27, R1C3 | IC50 | > | 10 | uM | ALA3396644 | nM | ||||
| 11. | ALA2180410 | Figure 27, R1C3 | Selectivity Index | = | 79 | ALA3396643 | ||||||
| 12. | ALA2180410 | Figure 27, R1C3 | pIC50 | = | 6.74 | ALA3396559 | 6.74 | nM | Rattus norvegicus | |||
| 13. | ALA2180410 | Figure 27, R1C3 | CLH | = | 11 | microL/min/mg | ALA3396560 | mL.min-1.g-1 | Rattus norvegicus | |||
| 14. | ALA2180410 | Figure 27, R1C3 | ERH | = | 0.22 | ALA3396561 | Rattus norvegicus | |||||
| 15. | ALA2180410 | Figure 27, R1C3 | ED50 | = | 1.02 | mg kg-1 | ALA3396562 | mg.kg-1 | Rattus norvegicus | |||
| 16. | ALA2180410 | Figure 27, R1C3 | ED50 | = | 1.1 | mg kg-1 | ALA3396564 | mg.kg-1 | Rattus norvegicus | |||
| 17. | ALA2180410 | Figure 27, R1C3 | ED50 | = | 1.1 | mg kg-1 | ALA2187447 | mg.kg-1 | Rattus norvegicus | |||
| 18. | ALA2180410 | Figure 27, R1C3 | ED50 | = | 1.54 | mg kg-1 | ALA2182996 | mg.kg-1 | Rattus norvegicus | |||
| 19. | ALA2180410 | Figure 27, R1C3 | ED50 | = | 2 | mg kg-1 | ALA2182997 | mg.kg-1 | Rattus norvegicus | |||
| 20. | ALA2180410 | Figure 27, R1C3 | IC50 | = | 190 | nM | ALA2187449 | 6.72 | nM | Rattus norvegicus |
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